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田中 俊光
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- A Rare Case of Primary Hepatic Undifferentiated Pleomorphic Sarcoma: Exploring Cancer-related Gene Mutations.
Hiroyuki Suzuki; Michitaka Fukuda; Tomotake Shirono; Reiichiro Kondo; Toshimitsu Tanaka; Takashi Niizeki; Jun Akiba; Hironori Koga; Takumi Kawaguchi
Internal medicine (Tokyo, Japan), 2024年11月08日 - Efficacy of timing‑dependent infusion of nivolumab in patients with advanced gastric cancer.
Toshimitsu Tanaka; Hiroyuki Suzuki; Shotaro Yamaguchi; Yasutaka Shimotsuura; Sachiko Nagasu; Kenta Murotani; Fumihiko Fujita; Takumi Kawaguchi; Keisuke Miwa
Oncology letters, 2024年10月
筆頭著者 - Ex-vivo expanded CD34+ cell transplantation alleviates fibrotic liver injury via innate immune modulation in metabolic dysfunction-associated steatohepatitis mice.
Atsutaka Masuda; Toru Nakamura; Hideki Iwamoto; Hiroyuki Suzuki; Takahiko Sakaue; Toshimitsu Tanaka; Yasuko Imamura; Nobuyuki Mori; Hironori Koga; Takumi Kawaguchi
Cytotherapy, 2024年08月 - Anti-PD-L1 antibodies promote cellular proliferation by activating the PD-L1-AXL signal relay in liver cancer cells.
Toshimitsu Tanaka; Hironori Koga; Hiroyuki Suzuki; Hideki Iwamoto; Takahiko Sakaue; Atsutaka Masuda; Toru Nakamura; Jun Akiba; Hirohisa Yano; Takuji Torimura; Takumi Kawaguchi
Hepatology international, 2024年06月
筆頭著者 - Fibroblast growth factor inhibition by molecular-targeted agents mitigates immunosuppressive tissue microenvironment in hepatocellular carcinoma.
Hiroyuki Suzuki; Hideki Iwamoto; Toshimitsu Tanaka; Takahiko Sakaue; Yasuko Imamura; Atsutaka Masuda; Toru Nakamura; Hironori Koga; Yujin Hoshida; Takumi Kawaguchi
Hepatology international, 2024年04月 - Changing from NAFLD to MASLD: Similar prognosis of unresectable extrahepatic gastrointestinal cancer under chemotherapy between NAFLD and MASLD.
Hiroyuki Suzuki; Toshimitsu Tanaka; Shotaro Yamaguchi; Keisuke Miwa; Takumi Kawaguchi
Journal of hepatology, 2024年04月
責任著者 - A tumor endothelial cell-specific microRNA replacement therapy for hepatocellular carcinoma.
Hideki Iwamoto; Hiroyuki Suzuki; Atsutaka Masuda; Takahiko Sakaue; Toru Nakamura; Toshimitsu Tanaka; Miwa Sakai; Yasuko Imamura; Hirohisa Yano; Takuji Torimura; Hironori Koga; Kaori Yasuda; Masakatsu Tsurusaki; Takahiro Seki; Takumi Kawaguchi
iScience, 2024年02月16日 - Patient Satisfaction Survey on Portable Infusion Pumps for Colorectal Cancer Chemotherapy: Hard-Shelled or Soft-Shelled?
Taku Yamada; Taketomo Kikuchi; Sachiko Nagasu; Kayoko Hashimoto; Eri Furukawa; Hirokazu Matsumoto; Kazuki Tsutsumi; Toshimitsu Tanaka; Miho Kugishima; Takumi Kawaguchi; Fumihiko Fujita; Kyouko Higuchi; Keisuke Miwa
Patient preference and adherence, 2024年 - Pancreatic Juice-Derived microRNA-4516 and microRNA-4674 as Novel Biomarkers for Pancreatic Ductal Adenocarcinoma.
Takahiko Sakaue; Hironori Koga; Hideki Iwamoto; Toru Nakamura; Atsutaka Masuda; Toshimitsu Tanaka; Hiroyuki Suzuki; Hideya Suga; Shingo Hirai; Toru Hisaka; Yoshiki Naito; Keisuke Ohta; Kei-Ichiro Nakamura; Karuppaiyah Selvendiran; Yoshinobu Okabe; Takuji Torimura; Takumi Kawaguchi
Gastro hep advances, 2024年 - High intramuscular adipose tissue content was a favorable prognostic factor in patients with advanced gastric cancer treated with nivolumab monotherapy.
Toshimitsu Tanaka; Keisuke Miwa; Yasutaka Shimotsuura; Sachiko Nagasu; Hirona Shigyou; Keisuke Hirota; Shunji Koya; Yoshito Akagi; Takumi Kawaguchi
Journal of gastroenterology and hepatology, 2023年10月
筆頭著者, 責任著者 - Safety of Early Bevacizumab Administration after Central Venous Port Placement for Patients with Colorectal Cancer.
Hirona Shigyo; Hiroyuki Suzuki; Toshimitsu Tanaka; Etsuko Moriyama; Yasutaka Shimotsuura; Sachiko Nagasu; Hideki Iwamoto; Yoshito Akagi; Kenta Murotani; Takumi Kawaguchi; Keisuke Miwa
Cancers, 2023年04月12日
責任著者 - Tumor-derived insulin-like growth factor-binding protein-1 contributes to resistance of hepatocellular carcinoma to tyrosine kinase inhibitors.
Hiroyuki Suzuki; Hideki Iwamoto; Takahiro Seki; Toru Nakamura; Atsutaka Masuda; Takahiko Sakaue; Toshimitsu Tanaka; Yasuko Imamura; Takashi Niizeki; Masahito Nakano; Shigeo Shimose; Tomotake Shirono; Yu Noda; Naoki Kamachi; Miwa Sakai; Kazutoyo Morita; Masamichi Nakayama; Tomoharu Yoshizumi; Ryoko Kuromatsu; Hirohisa Yano; Yihai Cao; Hironori Koga; Takuji Torimura
Cancer communications (London, England), 2023年04月 - T-cell factor-4 variants regulate PD-L1 expression in liver cancer cells
TOSHIMITSU TANAKA
Cancer Research, 2023年 - Evaluation of the nematode C. elegans cancer test (N-NOSE) in thyroid cancer
TOSHIMITSU TANAKA
Annals of Oncology, 2023年 - Early monocyte elevation after atezolizumab plus bevacizumab therapy could be a therapeutic biomarker in HCC
TOSHIMITSU TANAKA
Cancer Science, 2023年 - A case of complete response to entrectinib in NTRK fusion gene-positive parotid carcinoma
TOSHIMITSU TANAKA
Annals of Oncology, 2023年 - Case Report: A case of complete response to entrectinib in NTRK fusion gene-positive parotid gland cancer.
Etsuko Moriyama; Sachiko Nagasu; Toshimitsu Tanaka; Yasutaka Shimotsuura; Takeharu Ono; Hirohito Umeno; Jun Akiba; Akihiko Kawahara; Fumihiko Fujita; Takumi Kawaguchi; Keisuke Miwa
Frontiers in oncology, 2023年 - Case report: A case of fulminant type 1 diabetes mellitus after COVID-19 vaccination during treatment of advanced gastric cancer: pitfall in managing immune-related adverse events.
Toshimitsu Tanaka; Sachiko Nagasu; Takuya Furuta; Mizuki Gobaru; Hiroyuki Suzuki; Yasutaka Shimotsuura; Jun Akiba; Masatoshi Nomura; Fumihiko Fujita; Takumi Kawaguchi; Keisuke Miwa
Frontiers in oncology, 2023年
筆頭著者 - Hyperlipidemia as a risk factor for Trousseau syndrome-related cerebral infarction in patients with advanced gastrointestinal cancer.
Toshimitsu Tanaka; Hiroyuki Suzuki; Keisuke Miwa; Tomoyuki Ushijima; Sachiko Nagasu; Masaru Fukahori; Kaito Ishii; Toru Nakamura; Hideki Iwamoto; Atsutaka Masuda; Takahiko Sakaue; Hironori Koga; Yoshito Akagi; Kenta Murotani; Takuji Torimura
Oncology letters, 2022年09月
筆頭著者 - 抗PD-L1抗体による肝癌細胞増殖機構の解明
田中 俊光; 古賀 浩徳; 鈴木 浩之; 岩本 英希; 阪上 尊彦; 増田 篤高; 中村 徹; 秋葉 純; 矢野 博久; 鳥村 拓司
日本消化器病学会雑誌, 2022年03月 - NOVEL EXOSOMAL MICRORNAS SPECIFIC FOR PANCREATIC DUCTAL ADENOCARCINOMA IDENTIFIED FROM PANCREATIC JUICE
TOSHIMITSU TANAKA
Gastroenterology, 2022年 - DNA Methylation in Noncancerous Liver Tissues as Biomarker for Multicentric Occurrence of Hepatitis C Virus-Related Hepatocellular Carcinoma.
Hiroyuki Suzuki; Hideki Iwamoto; Ken Yamamoto; Mai Tsukaguchi; Toru Nakamura; Atsutaka Masuda; Takahiko Sakaue; Toshimitsu Tanaka; Takashi Niizeki; Shusuke Okamura; Shigeo Shimose; Tomotake Shirono; Yu Noda; Naoki Kamachi; Ryoko Kuromatsu; Toru Hisaka; Hirohisa Yano; Hironori Koga; Takuji Torimura
Gastro hep advances, 2022年 - Case report: Changes in serum bevacizumab concentration in a hemodialysis patient with unresectable colorectal cancer treated with FOLFIRI plus bevacizumab.
Toshimitsu Tanaka; Hiroyuki Suzuki; Tomoyuki Ushijima; Sachiko Nagasu; Yoshito Akagi; Takumi Kawaguchi; Keisuke Miwa
Frontiers in oncology, 2022年
筆頭著者 - Efficacy and tolerability of Sorafenib plus metronomic chemotherapy S-1 for advanced hepatocellular carcinoma in preclinical and clinical assessments.
Hiroyuki Suzuki; Hideki Iwamoto; Masahito Nakano; Toru Nakamura; Atsutaka Masuda; Takahiko Sakaue; Toshimitsu Tanaka; Dan Nakano; Ryoko Kuromatsu; Takashi Niizeki; Shusuke Okamura; Shigeo Shimose; Tomotake Shirono; Yu Noda; Naoki Kamachi; Hirohisa Yano; Atsushi Kawaguchi; Hironori Koga; Takuji Torimura
Translational oncology, 2021年11月 - A phase II study of gemcitabine plus nab-paclitaxel as first-line therapy for locally advanced pancreatic cancer.
Masaru Fukahori; Keisuke Miwa; Kenta Murotani; Yoshiki Naito; Tomoyuki Ushijima; Takahiko Sakaue; Toshimitsu Tanaka; Sachiko Nagasu; Hideya Suga; Tatsuyuki Kakuma; Yoshinobu Okabe; Takuji Torimura
Medicine, 2021年05月21日 - QOL改善を目指した自家末梢血CD34陽性細胞移植による肝硬変治療開発
中村 徹; 増田 篤高; 岩本 英希; 鈴木 浩之; 田中 俊光; 阪上 尊彦; 古賀 浩徳; 鳥村 拓司
肝臓, 2021年04月 - FGFR INHIBITION ALTERS 'COLD TUMOR' INTO 'HOT TUMOR' IN IMMUNE SYNGENEIC ORTHOTOPIC HEPATOCELLULAR CARCINOMA
TOSHIMITSU TANAKA
Hepatology, 2021年 - Elevated serum IGFBP-1 levels after lenvatinib treatment reflect intratumoral ischemia
TOSHIMITSU TANAKA
Cancer Science, 2021年 - Anti-PD-L1 antibodies promote proliferation of sarcomatous liver cancer cells
TOSHIMITSU TANAKA
Cancer Science, 2021年 - Precise evaluation of TCF-4 isoform expressions in tumors derived from digestive organs
TOSHIMITSU TANAKA
Cancer Science, 2021年 - Character Input Method Working on 1-in. Round Screen for Tiny Smartwatches
TOSHIMITSU TANAKA
Lecture Notes in Computer Science, 2021年 - レンバチニブ投与により上昇する血清IGFBP-1は腫瘍内虚血を反映する
鈴木 浩之; 岩本 英希; 阪上 尊彦; 田中 俊光; 古賀 浩徳; 鳥村 拓司
日本癌学会総会記事, 2020年10月 - 切除不能局所進行膵癌に対するGemcitabine+nab-Paclitaxel療法の単施設第II相試験
深堀 理; 牛島 知之; 岡部 義信; 重藤 宏太; 田中 俊光; 長主 祥子; 阪上 尊彦; 島松 裕; 安元 真希子; 三輪 啓介; 鶴田 修; 鳥村 拓司
日本消化器病学会雑誌, 2020年10月 - Promotion of liver regeneration and anti‑fibrotic effects of the TGF‑β receptor kinase inhibitor galunisertib in CCl4‑treated mice.
Atsutaka Masuda; Toru Nakamura; Mitsuhiko Abe; Hideki Iwamoto; Takahiko Sakaue; Toshimitsu Tanaka; Hiroyuki Suzuki; Hironori Koga; Takuji Torimura
International journal of molecular medicine, 2020年07月 - Profiles Combining Muscle Atrophy and Neutrophil-to-Lymphocyte Ratio Are Associated with Prognosis of Patients with Stage IV Gastric Cancer.
Kota Shigeto; Takumi Kawaguchi; Shunji Koya; Keisuke Hirota; Toshimitsu Tanaka; Sachiko Nagasu; Masaru Fukahori; Tomoyuki Ushijima; Hiroo Matsuse; Keisuke Miwa; Koji Nagafuji; Takuji Torimura
Nutrients, 2020年06月24日 - Weekends-Off Lenvatinib for Unresectable Hepatocellular Carcinoma Improves Therapeutic Response and Tolerability toward Adverse Events.
Hideki Iwamoto; Hiroyuki Suzuki; Shigeo Shimose; Takashi Niizeki; Masahito Nakano; Tomotake Shirono; Shusuke Okamura; Yu Noda; Naoki Kamachi; Toru Nakamura; Atsutaka Masuda; Takahiko Sakaue; Toshimitsu Tanaka; Dan Nakano; Miwa Sakai; Taizo Yamaguchi; Ryoko Kuromatsu; Hironori Koga; Takuji Torimura
Cancers, 2020年04月19日 - レンバチニブは腫瘍免疫微小環境を免疫学的'cold'から'hot'へ変化させる
鈴木 浩之; 岩本 英希; 中村 徹; 増田 篤高; 阪上 尊彦; 田中 俊光; 中野 暖; 古賀 浩徳; 鳥村 拓司
肝臓, 2020年04月 - Pancreatic juice biomarker for detection of early stage pancreatic cancer using tumor-specific exosomal microRNAs
TOSHIMITSU TANAKA
Cancer Research, 2020年 - Opposite functions of Claudin-2 involving Wnt signaling in liver cancer cells
TOSHIMITSU TANAKA
Cancer Research, 2020年 - Glycosylation of ascites-derived exosomal CD133: a potential prognostic biomarker in patients with advanced pancreatic cancer.
Takahiko Sakaue; Hironori Koga; Hideki Iwamoto; Toru Nakamura; Yu Ikezono; Mitsuhiko Abe; Fumitaka Wada; Atsutaka Masuda; Toshimitsu Tanaka; Masaru Fukahori; Tomoyuki Ushijima; Yuutarou Mihara; Yoshiki Naitou; Yoshinobu Okabe; Tatsuyuki Kakuma; Keisuke Ohta; Kei-Ichiro Nakamura; Takuji Torimura
Medical molecular morphology, 2019年12月 - Modified FOLFOX6+Panitumumab療法中に高アンモニア血症による意識障害を発症した切除不能進行大腸癌の1例
田中 俊光; 三輪 啓介; 深堀 理; 四方田 隆任; 阪上 尊彦; 長主 祥子; 牛島 知之; 古賀 浩徳; 鳥村 拓司
癌と化学療法, 2019年02月 - [A Case of Chemotherapy-Induced Hyperammonemic Encephalopathy in a Patient with Metastatic Colon Cancer].
Toshimitsu Tanaka; Keisuke Miwa; Masaru Fukahori; Takatou Yomoda; Takahiko Sakaue; Sachiko Nagasu; Tomoyuki Ushijima; Hironori Koga; Takuji Torimura
Gan to kagaku ryoho. Cancer & chemotherapy, 2019年02月 - 【大腸内分泌細胞腫瘍-WHOの考え方と日本の考え方】大腸内分泌細胞腫瘍の薬物療法
深堀 理; 三輪 啓介; 長主 祥子; 下津浦 康隆; 田中 俊光; 牛島 知之; 阪上 尊彦; 岡部 義信; 鶴田 修
Intestine, 2019年01月 - Experience of lenvatinib therapy for patients with differentiated thyroid cancer in our hospital
TOSHIMITSU TANAKA
Annals of Oncology, 2019年 - CD34-POSITIVE CELL TRANSPLANTATION IMPROVES LIVER FIBROSIS IN A MOUSE MODEL OF NON-ALCOHOLIC STEATOHEPATITIS
TOSHIMITSU TANAKA
Hepatology, 2019年 - INVOLVEMENT OF WNT SIGNALING IN TWO-FACED ACTIONS OF CLAUDIN-2 IN LIVER CANCER CELLS
TOSHIMITSU TANAKA
Hepatology, 2019年 - 癌性腹水由来exosome中CD133に対する糖鎖修飾が進行膵癌患者の予後予測のバイオマーカーとなり得る
阪上 尊彦; 古賀 浩徳; 岩本 英希; 中村 徹; 安倍 満彦; 和田 史孝; 増田 篤高; 田中 俊光; 深堀 理; 牛島 知之; 岡部 義信; 鳥村 拓司
日本消化器病学会雑誌, 2018年10月 - High expression of CD44v9 and xCT in chemoresistant hepatocellular carcinoma: Potential targets by sulfasalazine.
Fumitaka Wada; Hironori Koga; Jun Akiba; Takashi Niizeki; Hideki Iwamoto; Yu Ikezono; Toru Nakamura; Mitsuhiko Abe; Atsutaka Masuda; Takahiko Sakaue; Toshimitsu Tanaka; Tatsuyuki Kakuma; Hirohisa Yano; Takuji Torimura
Cancer science, 2018年09月 - The Wnt target gene CLAUDIN-2 regulates tumorigenesis and stemness in human liver cancer cells
TOSHIMITSU TANAKA
Cancer Research, 2018年 - HES1 critically regulates sphere-forming ability and tumorigenesis in WNT signal-engineered liver cancer cells
TOSHIMITSU TANAKA
Cancer Science, 2018年 - Proteomic Discovery of Brain-Derived Neurotrophic Factor in Serum and Bile Ducts in Cholestasis
TOSHIMITSU TANAKA
Hepatology, 2018年 - CD44v9 expression in surviving liver cancer cells treated with hepatic arterial infusion chemoembolization therapy
TOSHIMITSU TANAKA
Cancer Science, 2018年 - Claudin-2 Activates LKB1-AMPK Signals, Thereby Inducing Cell-Cycle Arrest and Autophagy in Liver Cancer Cells
古賀 浩徳; 和田 史孝; 阪上 尊彦; 岩本 英希; 安倍 満彦; 鳥村 拓司
Hepatology, 2018年 - STAT3 deficiency prevents hepatocarcinogenesis and promotes biliary proliferation in thioacetamide-induced liver injury.
Mitsuhiko Abe; Takafumi Yoshida; Jun Akiba; Yu Ikezono; Fumitaka Wada; Atsutaka Masuda; Takahiko Sakaue; Toshimitsu Tanaka; Hideki Iwamoto; Toru Nakamura; Michio Sata; Hironori Koga; Akihiko Yoshimura; Takuji Torimura
World journal of gastroenterology, 2017年10月07日 - 肝動注化学塞栓療法後に残存した肝細胞癌におけるCD44v9の発現の検討
和田 史孝; 古賀 浩徳; 秋葉 純; 池園 友; 中村 徹; 安倍 満彦; 岩本 英希; 阪上 尊彦; 増田 篤高; 田中 俊光; 矢野 博久; 鳥村 拓司
日本癌学会総会記事, 2017年09月 - HES1はWNTシグナル改変肝癌細胞においてスフィア形成能や造腫瘍能を決定的に制御する
古賀 浩徳; 中村 徹; 和田 史孝; 岩本 英希; 増田 篤高; 阪上 尊彦; 田中 俊光; 安倍 満彦; 秋葉 純; 矢野 博久; 鳥村 拓司
日本癌学会総会記事, 2017年09月 - 膵癌癌性腹水由来エクソソームに内在するCD133糖鎖の臨床的意義
阪上 尊彦; 古賀 浩徳; 中村 徹; 池園 友; 和田 史孝; 安倍 満彦; 岩本 英希; 増田 篤高; 田中 俊光; 深堀 理; 岡部 義信; 鳥村 拓司
日本消化器病学会雑誌, 2017年09月 - The Wnt Target Gene CLAUDIN-2 Regulates Tumorigenesis of Combined Hepatocellular-Cholangiocarcinoma Cells
TOSHIMITSU TANAKA
Hepatology, 2017年 - Targeting CD44v9-xCT system by sulfasalazine to overcome cisplatin resistance in human liver cancer cells
TOSHIMITSU TANAKA
Hepatology, 2017年 - Long term outcome of autologous G-CSF mobilized PB-CD34+ cell therapy in patients with decompensated liver cirrhosis
TOSHIMITSU TANAKA
Hepatology, 2016年 - The Wnt effector T-CELL FACTOR-4 isoform activates Notch signaling via upregulating CLAUDIN-2 in human liver cancer cells
TOSHIMITSU TANAKA
Hepatology, 2016年 - Decreased serum levels of immunoglobulin A, immunoglobulin M and immunoglobulin G in a patient with primary biliary cirrhosis: A case report.
Takumi Kawaguchi; Toshimitsu Tanaka; Michitoshi Hashiguchi; Hiroaki Miyoshi; Jun Akiba; Masayoshi Kage; Hirohisa Yano; Koichi Ohshima; Takashi Okamura; Michio Sata
Hepatology research : the official journal of the Japan Society of Hepatology, 2014年10月
- 化学療法前の原発不明癌では栄養指標が重要な予後予測におけるバイオマーカーとなる
山口 翔太郎; 田中 俊光; 長主 祥子; 下津浦 康隆; 藤田 文彦; 室谷 健太; 川口 巧; 三輪 啓介
日本癌治療学会学術集会抄録集, 2024年10月 - 肝細胞癌に対するレンバチニブ治療のバイオマーカー探索および耐性獲得に関与するIGFBP-1についての検討
鈴木浩之; 岩本英希; 中村徹; 増田篤高; 阪上尊彦; 田中俊光; 中野暖; 新関敬; 中野聖士; 岡村修祐; 下瀬茂男; 城野智毅; 野田悠; 蒲池直紀; 黒松亮子; 古賀浩徳; 鳥村拓司
肝臓, 2021年
