Body Muscle-to-Fat Ratio (BMFR) as a Promising Anthropometric Index for Use in the Evaluation of Insulin Resistance and Metabolic Disease Risk: a Narrative Review.
Noboru Kurinami; Seigo Sugiyama; Akira Yoshida; Kunio Hieshima; Tomoko Suzuki; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouchi; Kenji Ashida; Masatoshi Nomura; Hideaki Jinnouchi
Current obesity reports, 2025年10月29日

Early Dose Escalation of Tirzepatide after Switching from Semaglutide in Type 2 Diabetes Mellitus.
Noboru Kurinami; Masafumi Takada; Seigo Sugiyama; Akira Yoshida; Kunio Hieshima; Tomoko Suzuki; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouchi; Kenji Ashida; Masatoshi Nomura; Hideaki Jinnouchi
Endocrinology and metabolism (Seoul, Korea), 2025年10月15日

High Frequency of Defecation under Metformin Use May Be a Potential Glucose-lowering Factor Independent of the Dose-dependent Effect of Metformin in Patients with Type 2 Diabetes Mellitus.
Kunio Hieshima; Seigo Sugiyama; Akira Yoshida; Noboru Kurinami; Tomoko Suzuki; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouchi; Tomio Jinnouchi; Hideaki Jinnouchi
Internal medicine (Tokyo, Japan), 2025年05月15日

Clinical Factors Associated with Body-weight Reduction Induced by Semaglutide 1.0 mg Weekly in Patients with Type 2 Diabetes Mellitus.
Noboru Kurinami; Masafumi Takada; Kenji Ashida; Seigo Sugiyama; Akira Yoshida; Kunio Hieshima; Tomoko Suzuki; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouchi; Masatoshi Nomura; Hideaki Jinnouchi
JMA journal, 2025年04月28日

Impact of Albuminuria and Renal Dysfunction on the Anemia-Improving Effect of SGLT2 Inhibitors in Patients With Type 2 Diabetes: A Real-World Observational Study.
Ayami Kajiwara-Morita; Kentaro Oniki; Akira Yoshida; Noboru Kurinami; Tomoko Suzuki; Fumio Miyamoto; Kunio Hieshima; Seigo Sugiyama; Keizo Kajiwara; Katsunori Jinnouchi; Junji Saruwatari; Hideaki Jinnouchi
Journal of diabetes research, 2025年

Calculated estimation of the metabolic clearance rate of insulin measured by glucose clamp examination in out-patient clinical practice.
Noboru Kurinami; Seigo Sugiyama; Akira Yoshida; Kunio Hieshima; Tomoko Suzuki; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouchi; Hideaki Jinnouchi
Diabetology international, 2024年10月

Severe periodontal disease in Japanese patients with high HbA1c levels: a cross-sectional study.
Noboru Kurinami; Kenji Ashida; Seigo Sugiyama; Yoko Morito; Akira Yoshida; Kunio Hieshima; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouchi; Hideaki Jinnouchi; Masatoshi Nomura
Diabetology international, 2024年07月

Reduced Number of Remaining or Healthy Teeth in Patients with Type 2 Diabetes Mellitus: A Cross-sectional Study Assessed by Dentists or Dental Hygienists in Japan.
Noboru Kurinami; Kenji Ashida; Seigo Sugiyama; Yoko Morito; Nao Hasuzawa; Akira Yoshida; Ayami Morita; Kunio Hieshima; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouchi; Tomio Jinnouchi; Hideaki Jinnouchi; Masatoshi Nomura
Internal medicine (Tokyo, Japan), 2023年

Potential Identification of Type 2 Diabetes with Elevated Insulin Clearance.
Seigo Sugiyama; Hideaki Jinnouchi; Kunio Hieshima; Noboru Kurinami; Katsunori Jinnouchi; Akira Yoshida; Tomoko Suzuki; Keizo Kajiwara; Fumio Miyamoto; Tomio Jinnouchi
NEJM evidence, 2022年04月

Changes in urinary glucose concentration and body weight in patients treated with the selective SGLT2 inhibitor luseogliflozin.
Hideaki Jinnouchi; Akira Yoshida; Hiromi Tsuyuno; Kiyoko Iwamoto; Seigo Sugiyama; Kunio Hieshima; Keizo Kajiwara; Noboru Kurinami; Tomoko Suzuki; Katsunori Jinnouchi; Tomio Jinnouchi
Diabetes research and clinical practice, 2021年12月

Body Muscle-to-Fat Ratio, Rather Than Fat-to-Muscle Ratio, Significantly Correlates With Measured Insulin Resistance in Patients With Type 2 Diabetes Mellitus.
Noboru Kurinami; Seigo Sugiyama; Akira Yoshida; Kunio Hieshima; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouch; Tomio Jinnouchi; Masatoshi Nomura; Hideaki Jinnouchi
Journal of clinical medicine research, 2021年07月

A Non-obese, Treatment-Naive Japanese Diabetic Patient With Elevated Insulin Clearance and Hyperglycemia Under Enhanced Insulin Sensitivity and Increased Insulin Secretion: Elevated Insulin Clearance as Type 2 Japanese Diabetes Mellitus (T2JDM).
Seigo Sugiyama; Hideaki Jinnouchi; Kunio Hieshima; Noboru Kurinami; Katsunori Jinnouchi
Cureus, 2021年04月07日

Characteristics of nephropathy in severely obese Japanese patients complicated with type 2 diabetes mellitus: a cross-sectional cohort study.
Noboru Kurinami; Seigo Sugiyama; Hiroko Ijima; Akira Yoshida; Kunio Hieshima; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouchi; Tomio Jinnouchi; Masatoshi Nomura; Hideaki Jinnouchi
Endocrine, 2020年12月

Initial Acute Decline in Estimated Glomerular Filtration Rate After Sodium-Glucose Cotransporter-2 Inhibitor in Patients With Chronic Kidney Disease.
Seigo Sugiyama; Akira Yoshida; Kunio Hieshima; Noboru Kurinami; Katsunori Jinnouchi; Motoko Tanaka; Tomoko Suzuki; Fumio Miyamoto; Keizo Kajiwara; Tomio Jinnouchi; Hideaki Jinnouchi
Journal of clinical medicine research, 2020年11月

Elevation of the renal threshold for glucose is associated with insulin resistance and higher glycated hemoglobin levels.
Kunio Hieshima; Seigo Sugiyama; Akira Yoshida; Noboru Kurinami; Tomoko Suzuki; Hiroko Ijima; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouchi; Tomio Jinnouchi; Hideaki Jinnouchi
Journal of diabetes investigation, 2020年05月

Type 2 Diabetes Remission and Substantial Body Weight Reduction Achieved with Metformin and a Sodium-Glucose Cotransporter 2 Inhibitor.
Seigo Sugiyama; Hideaki Jinnouchi; Kunio Hieshima; Noboru Kurinami; Katsunori Jinnouchi
Cureus, 2020年02月26日

Body muscle-to-fat ratio gender-specific cut-off values for impaired insulin sensitivity in patients with treatment-naïve type 2 diabetes mellitus.
Noboru Kurinami; Seigo Sugiyama; Akira Yoshida; Kunio Hieshima; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouch; Tomio Jinnouchi; Hideaki Jinnouchi
Endocrine, 2019年12月

Renoprotective Effects of Additional SGLT2 inhibitor Therapy in Patients With Type 2 Diabetes Mellitus and Chronic Kidney Disease Stages 3b-4: A Real World Report From A Japanese Specialized Diabetes Care Center.
Seigo Sugiyama; Hideaki Jinnouchi; Akira Yoshida; Kunio Hieshima; Noboru Kurinami; Katsunori Jinnouchi; Motoko Tanaka; Tomoko Suzuki; Fumio Miyamoto; Keizo Kajiwara; Tomio Jinnouchi
Journal of clinical medicine research, 2019年04月

Clinical usefulness of the body muscle-to-fat ratio for screening obstructive sleep apnea syndrome in patients with inadequately controlled type 2 diabetes mellitus.
Noboru Kurinami; Seigo Sugiyama; Hiroko Ijima; Akira Yoshida; Kunio Hieshima; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouch; Tomio Jinnouchi; Hideaki Jinnouchi
Diabetes research and clinical practice, 2018年09月

The SGLT2 Inhibitor Dapagliflozin Significantly Improves the Peripheral Microvascular Endothelial Function in Patients with Uncontrolled Type 2 Diabetes Mellitus.
Seigo Sugiyama; Hideaki Jinnouchi; Noboru Kurinami; Kunio Hieshima; Akira Yoshida; Katsunori Jinnouchi; Hiroyuki Nishimura; Tomoko Suzuki; Fumio Miyamoto; Keizo Kajiwara; Tomio Jinnouchi
Internal medicine (Tokyo, Japan), 2018年08月01日

Dapagliflozin significantly reduced liver fat accumulation associated with a decrease in abdominal subcutaneous fat in patients with inadequately controlled type 2 diabetes mellitus.
Noboru Kurinami; Seigo Sugiyama; Akira Yoshida; Kunio Hieshima; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouch; Tomio Jinnouchi; Hideaki Jinnouchi
Diabetes research and clinical practice, 2018年08月

Dapagliflozin Reduces Fat Mass without Affecting Muscle Mass in Type 2 Diabetes.
Seigo Sugiyama; Hideaki Jinnouchi; Noboru Kurinami; Kunio Hieshima; Akira Yoshida; Katsunori Jinnouchi; Hiroyuki Nishimura; Tomoko Suzuki; Fumio Miyamoto; Keizo Kajiwara; Tomio Jinnouchi
Journal of atherosclerosis and thrombosis, 2018年06月01日

Impact of Dapagliflozin Therapy on Renal Protection and Kidney Morphology in Patients With Uncontrolled Type 2 Diabetes Mellitus.
Seigo Sugiyama; Hideaki Jinnouchi; Noboru Kurinami; Kunio Hieshima; Akira Yoshida; Katsunori Jinnouchi; Motoko Tanaka; Hiroyuki Nishimura; Tomoko Suzuki; Fumio Miyamoto; Keizo Kajiwara; Tomio Jinnouchi
Journal of clinical medicine research, 2018年06月

Smoking Cessation Ameliorates Microalbuminuria With Reduction of Blood Pressure and Pulse Rate in Patients With Already Diagnosed Diabetes Mellitus.
Kunio Hieshima; Tomoko Suzuki; Seigo Sugiyama; Noboru Kurinami; Akira Yoshida; Fumio Miyamoto; Keizo Kajiwara; Tomio Jinnouchi; Hideaki Jinnouchi
Journal of clinical medicine research, 2018年06月

Ratio of muscle mass to fat mass assessed by bioelectrical impedance analysis is significantly correlated with liver fat accumulation in patients with type 2 diabetes mellitus.
Noboru Kurinami; Seigo Sugiyama; Ayami Morita; Akira Yoshida; Kunio Hieshima; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouch; Tomio Jinnouchi; Hideaki Jinnouchi
Diabetes research and clinical practice, 2018年05月

Clinical Factors Associated with Initial Decrease in Body-Fat Percentage Induced by Add-on Sodium-Glucose Co-transporter 2 Inhibitors in Patient with Type 2 Diabetes Mellitus.
Noboru Kurinami; Seigo Sugiyama; Hiroyuki Nishimura; Ayami Morita; Akira Yoshida; Kunio Hieshima; Fumio Miyamoto; Keizo Kajiwara; Katsunori Jinnouchi; Tomio Jinnouchi; Hideaki Jinnouchi
Clinical drug investigation, 2018年01月

Correlation of body muscle/fat ratio with insulin sensitivity using hyperinsulinemic-euglycemic clamp in treatment-naïve type 2 diabetes mellitus.
Noboru Kurinami; Seigo Sugiyama; Akira Yoshida; Kunio Hieshima; Fumio Miyamoto; Keizo Kajiwara; Tomio Jinnouchi; Hideaki Jinnouchi
Diabetes research and clinical practice, 2016年10月

Continuous Glucose Monitoring During Basal-Bolus Therapy Using Insulin Glargine 300 U mL(-1) and Glargine 100 U mL (-1) in Japanese People with Type 1 Diabetes Mellitus: A Crossover Pilot Study.
Hideaki Jinnouchi; Masayoshi Koyama; Atsushi Amano; Yoshinori Takahashi; Akira Yoshida; Kunio Hieshima; Seigo Sugiyama; Noboru Kurinami; Tomio Jinnouchi; Reinhard Becker
Diabetes therapy : research, treatment and education of diabetes and related disorders, 2015年06月

A pilot study of ezetimibe vs. atorvastatin for improving peripheral microvascular endothelial function in stable patients with type 2 diabetes mellitus.
Seigo Sugiyama; Hideaki Jinnouchi; Kunio Hieshima; Noboru Kurinami; Tomoko Suzuki; Fumio Miyamoto; Keizo Kajiwara; Kunihiko Matsui; Tomio Jinnouchi
Lipids in health and disease, 2015年04月23日

Liraglutide, a glucagon-like peptide-1 analog, increased insulin sensitivity assessed by hyperinsulinemic-euglycemic clamp examination in patients with uncontrolled type 2 diabetes mellitus.
Hideaki Jinnouchi; Seigo Sugiyama; Akira Yoshida; Kunio Hieshima; Noboru Kurinami; Tomoko Suzuki; Fumio Miyamoto; Keizo Kajiwara; Kunihiko Matsui; Tomio Jinnouchi
Journal of diabetes research, 2015年