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Nakayoshi Takaharu
Division of Cardiovascular Medicine Department of Internal Medicine
Assistant Professor
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総合内科専門医
循環器専門医
日本心血管インターベンション治療学会専門医
経カテーテル的大動脈弁置換術 実施認定医/指導医(Sapienシリーズ)
心臓リハビリテーション指導士
Research activity information
■ Paper
■ Research Themes
- Comparison of Vessel Responses Following Combined Sirolimus-Eluting and Endothelial Progenitor Cell Stent and Ultra-Thin Sirolimus-Eluting Stent Implantation by Serial Optical Coherence Tomography and Coronary Angioscopy: A Multicenter Observational Study.
Daisuke Nakamura; Isamu Mizote; Takayuki Ishihara; Yutaka Matsuhiro; Shota Okuno; Tatsuya Shiraki; Takuya Tsujimura; Naotaka Okamoto; Naoki Itaya; Takaharu Nakayoshi; Atsushi Kikuchi; Tsutomu Kawai; Yuhei Nojima; Mitsuyoshi Takahara; Takashi Morita; Shungo Hikosou; Daisaku Nakatani; Toshiaki Mano; Takahisa Yamada; Takahumi Ueno; Masami Nishino; Shinsuke Nanto; Yasushi Sakata
The American journal of cardiology, 23 Jan. 2025 - Impact of baseline yellow plaque assessed by coronary angioscopy on vascular response after stent implantation.
Takuya Tsujimura; Isamu Mizote; Takayuki Ishihara; Daisuke Nakamura; Naotaka Okamoto; Tatsuya Shiraki; Naoki Itaya; Mitsuyoshi Takahara; Takaharu Nakayoshi; Osamu Iida; Yosuke Hata; Masami Nishino; Takafumi Ueno; Daisaku Nakatani; Shungo Hikoso; Shinsuke Nanto; Toshiaki Mano; Yasushi Sakata
Journal of cardiology, Sep. 2024 - Mitral regurgitation is associated with similar loss of von Willebrand factor large multimers but lower frequency of anemia compared with aortic stenosis.
Hiroshi Takiguchi; Mizuki Miura; Shin-Ichi Shirai; Yoshimitsu Soga; Michiya Hanyu; Genichi Sakaguchi; Yoshiharu Soga; Yoshio Arai; Shin Watanabe; Takeshi Kimura; Hiroyuki Takahama; Satoshi Yasuda; Takaharu Nakayoshi; Yoshihiro Fukumoto; Nobuhiro Yaoita; Hiroaki Shimokawa; Ko Sakatsume; Yoshikatsu Saiki; Koichi Kaikita; Kenichi Tsujita; Toshihiro Tamura; Tsuyoshi Doman; Mihoko Yamashita; Misako Suzuki; Yuka Eura; Koichi Kokame; Masaki Hayakawa; Masanori Matsumoto; Noriyuki Okubo; Shingo Sugawara; Shin-Ichi Fujimaki; Yasunori Kawate; Kenji Ando; Hisanori Horiuchi
Research and practice in thrombosis and haemostasis, May 2024 - von Willebrand factor Ristocetin co-factor activity to von Willebrand factor antigen level ratio for diagnosis of acquired von Willebrand syndrome caused by aortic stenosis.
Noriyuki Okubo; Shingo Sugawara; Tohru Fujiwara; Ko Sakatsume; Tsuyoshi Doman; Mihoko Yamashita; Kota Goto; Masaki Tateishi; Misako Suzuki; Ryutaro Shirakawa; Yuka Eura; Koichi Kokame; Masaki Hayakawa; Masanori Matsumoto; Yasunori Kawate; Mizuki Miura; Hiroshi Takiguchi; Yoshimitsu Soga; Shinichi Shirai; Kenji Ando; Yoshio Arai; Takaharu Nakayoshi; Yoshihiro Fukumoto; Hiroyuki Takahama; Satoshi Yasuda; Toshihiro Tamura; Shin Watanabe; Takeshi Kimura; Nobuhiro Yaoita; Hiroaki Shimokawa; Yoshikatsu Saiki; Koichi Kaikita; Kenichi Tsujita; Shinji Yoshii; Hiroshi Nakase; Shin-Ichi Fujimaki; Hisanori Horiuchi
Research and practice in thrombosis and haemostasis, Jan. 2024 - Catheter-based examination for pulmonary microcirculatory function in patients with pulmonary hypertension.
Kazunori Yamaji; Ken-Ichiro Sasaki; Masaharu Nakano; Takumi Yoshiga; Masahiro Sasaki; Yoichi Sugiyama; Takashi Ishimatsu; Naoki Itaya; Takaharu Nakayoshi; Yoshiaki Mitsutake; Nobuhiro Tahara; Yoshihiro Fukumoto
PloS one, 2024 - 虚血性心不全への治療をどのように行うべきか? 低心機能の虚血性心疾患にPCIでどう挑むか? REVIVED-BCIS2の結果も踏まえて
吉賀 巧; 仲吉 孝晴; 福本 義弘
日本冠疾患学会誌, Nov. 2023 - Effects of Low-Dose Tadalafil in a Patient with Biventricular Heart Failure: A Case Report.
Shoko Kono; Jinya Takahashi; Koutatsu Shimozono; Jun Kumanomido; Norikazu Inoguchi; Shoichiro Nohara; Naoki Itaya; Takaharu Nakayoshi; Yoshihiro Fukumoto
The Tohoku journal of experimental medicine, 20 May 2023 - RTA-dh404 decreased oxidative stress in mice ischemic limbs and augmented efficacy of therapeutic angiogenesis by intramuscular injection of adipose-derived regenerative cells in the limbs.
Ishizaki Y, Sasaki KI, Yoshikawa T, Nakayoshi T, Sasaki M, Ohtsuka M, Hatada-Katakabe S, Takata Y, Fukumoto Y.
Eur J Pharmacol., Jan. 2023 - Impact of serial coronary stenoses on various coronary physiology indices.
E Ahn JM, Nakayoshi T, Hashikata T, Kashiyama K, Arashi H, Kweon J, Van't Veer M, Lyons J, Fearon WF.
Circ Cardiovasc Interv, Sep. 2022 - Comparison of 1-month and 12-month vessel responses between the polymer-free biolimus A9-coated stent and the durable polymer everolimus-eluting stent.
Ishihara T, Mizote I, Nakamura D, Okamoto N, Shiraki T, Itaya N, Tsujimura T, Takahara M, Nakayoshi T, Iida O, Hata Y, Nishino M, Ueno T, Nakatani D, Hikoso S, Nanto S, Mano T, Sakata Y; COLLABORATION Investigators.
Circulation Journal, Aug. 2022 - Risk factors and outcomes of recurrent drug-eluting stent thrombosis: Insights from the REAL-ST registry
Enomoto S, Kuramitsu S, Shinozaki T, Ohya M, Otake H, Yamanaka F, Shiomi H, Natsuaki M, Nakazawa G, Ando K, Kadota K, Saito S, Tamura T, Kimura T; REAL‐ST investigators †
J Am Heart Assoc, Apr. 2021 - A new beginning of aortic angioscopy in diagnosis and treatment in acute aortic syndrome?
Nakayoshi T, Ueno T
J Cardiol, Jul. 2020 - Low ankle brachial index predicts poor outcomes including target lesion revascularization during the long-term follow up after drug-eluting stent implantation for coronary artery disease.
Sasaki M, Mitsutake Y, Ueno T, Fukami A, Sasaki K, Yokoyama S, Ohtsuka M, Nakayoshi T, Itaya N, Chibana H, Sasaki M, Ishimatsu T, Kagiyama K, Fukumoto Y
J Cardiol, Mar. 2020 - Different vascular healing process between bioabsorbable polymer-coated everolimus-eluting stents versus bioresorbable vascular scaffold via optical coherence tomography and coronary angioscopy (the ENHANCE stusy: Endothelial Healing Assesment with Novel Coronary tEchonology).
Wan Ahmad WA, Nakayoshi T, Mahmood Zuhdi AS, Ismail MD, Zainal Abidin I, Kubo T, Akasaka T, Fukumoto Y, Ueno T
Heart Vessels, May 2019 - The use of bromocriptine for peripartum cardiomyopathy after twin delivery via oocyte donation.
Morikawa N, Nakayoshi T, Yoshimura H, Watanabe M, Kumanomido J, Furusho A, Fukui D, Eto K, Nishida N, Nishihara M, A Kamiya C, Fukumoto Y
Intern Med, Feb. 2019 - Hybrid training system-induced myokine secretion in healthy men.
Sasaki K, Ishizaki Y, Sasaki M, Nakayoshi T, Ohtsuka M, Matsuse H, Shiba N, Ueno T, Fukumoto Y
Cytokine, Nov. 2018 - DES留置後の血管反応の探求 -血管内視鏡から考える-
仲吉孝晴、上野高史
Coronary Intervention, 2017 - Interleukin-1β is associated with coronary endothelial dysfunction in patients with mTOR-inhibitor-eluting stent implantation.
Chibana H, Kajimoto H, Ueno T, Yokoyama S, Sasaki K, Ohtsuka M, Koiwaya H, Nakayoshi T, Mitsutake Y, Itaya N, Sasaki M, Fukumoto Y
Heart Vessels, Jan. 2017 - 〈Correspondence〉Differential angioscopic findings of neointimal coverage among first-, second-, and next generation drug-eluting stents.
Nakayoshi T, Ueno T, Sasaki KI, Yokoyama S, Ohtsuka M, Mitsutake Y, Itaya N, Chibana H, Sasaki M, Ishimatsu T, Kimura T, Fukumoto Y
Int J Cardiol, Nov. 2016 - TCT-410 different vascular healing process between bioabsorbable polymer-coated everolimus-eluting stents versus bioresorbable vascular scaffolds via optical coherence tomography and coronary angioscopy: Early Results from ENdothelial Healing Assessment With Novel Coronary tEchnology (ENHANCE study).
Wan Ahmad WA, Nakayoshi T, Mahmood Zuhdi AS, Ismail MD, Fukumoto Y, Ueno T
J Am Coll Cardiol, Nov. 2016 - Optical frequency-domain imaging and pulmonary angioscopy in chronic thromboembolic pulmonary hypertension.
Chibana H, Tahara N, Itaya N, Sasaki M, Sasaki M, Nakayoshi T, Ohtsuka M, Yokoyama S, Sasaki K, Ueno T, Fukumoto Y
Eur Heart J, Apr. 2016 - 急性冠症候群の臨床(ST上昇型心筋梗塞を除く) 5. 急性冠症候群の治療 (1)薬物療法
仲吉孝晴、知花英俊、上野高史
最新冠動脈疾患学 下 日本臨床, 2016 - Serial changes of coronary endothelial function and arterial healing after paclitaxel-eluting stent implantation.
Mitsutake Y, Ueno T, Ikeno F, Yokoyama S, Sasaki K, Nakayoshi T, Itaya N, Chibana H, Sasaki M, Fukumoto Y
Cardiovasc Interv Ther, Jan. 2016 - Plasma heat shock protein 27 is increased in renal dysfunction and habitual smoking in a Japanese general population.
Nakayoshi T, Adachi H, Ohbu-Murayama K, Enomono M, Fukami A, Kumagai E, Nakamura S, Nohara Y, Nakao E, Sasaki K, Fukumoto Y
J Cardiol, Jan. 2016 - 〈Correction〉FOXO4-knockdown suppresses oxidative stress-induced apoptosis of early pro-angiogenic cells and augments their neovascularization capacities in ischemic limbs.
Nakayoshi T, Sasaki K, Kajimoto H, Koiwaya H, Ohtsuka M, Ueno T, Chibana H, Itaya N, Sasaki M, Yokoyama S, Fukumoto Y, Imaizumi T
PLOS ONE, Apr. 2015 - Second-generation everolimus-eluting stents demonstrate better vascular function, less thrombus formation, and less yellow intima than first-generation drug-eluting stents.
Mitsutake Y, Ueno T, Ikeno F, Yokoyama S, Sasaki K, Ohtsuka M, Nakayoshi T, Itaya N, Chibana H, Sasaki M, Fukumoto Y
AsiaIntervention, 2015 - FOXO4-knockdown suppresses oxidative stress-induced apoptosis of early pro-angiogenic cells and augments their neovascularization capacities in ischemic limbs.
Nakayoshi T, Sasaki K, Kajimoto H, Koiwaya H, Ohtsuka M, Ueno T, Chibana H, Itaya N, Sasaki M, Yokoyama S, Fukumoto Y, Imaizumi T
PLOS ONE, Mar. 2014 - Platelet-derived microparticles augment the adhesion and neovascularization capacities of circulating angiogenic cells obtained from atherosclerotic patients.
Ohtsuka M, Sasaki K, Ueno T, Seki R, Nakayoshi T, Koiwaya H, Toyama Y, Yokoyama S, Mitsutake Y, Chibana H, Itaya N, Okamura T, Imaizumi T
Atherosclerosis, Apr. 2013 - 不安定プラークのインターベンション治療
仲吉孝晴、佐々木健一郎、上野高史
Heart View, 2013 - Ultrasound stimulation restores impaired neovascularization-related capacities of human circulating angiogenic cells.
Toyama Y, Sasaki K-I, Tachibana K, Ueno T, Kajimoto H, Yokoyama S, Ohtsuka M, Koiwaya H, Nakayoshi T, Mitsutake Y, Chibana H, Itaya N, Imaizumi T
Cardiovasc Res, Sep. 2012 - Coronary endothelial dysfunction distal to stent of first-generation drug-eluting stents.
Mitsutake Y, Ueno T, Yokoyama S, Sasaki K, Sugi Y, Toyama Y, Koiwaya H, Ohtsuka M, Nakayoshi T, Itaya N, Chibana H, Kakuma T, Imaizumi T
JACC Cardiovasc Interv, Sep. 2012 - Stent-anchored coil embolotherapy ?Novel treatment procedure for huge pulmonary arterio-venous malformation in hereditary hemorrhagic telangiectasia?
Koiwaya H, Kai H, Ueno T, Niiyama H, Takeuchi T, Ueda S-I, Gondo T, Kumagai E, Miyamoto M, Yokoyama S, Sasaki K-I, Toyama Y, Ohtsuka M, Mitsutake Y, Anegawa T, Nakayoshi T, Kudo Y, Suda K, Imaizumi T
Int J Cardiol, May 2012 - 地方二次病院での医原性冠動脈解離による心肺停止に対してドクターヘリにて専門医とPCPS搬送を行い救命できた1症例
仲吉孝晴、外山康之、横山晋二、上野高史、高松 学、佐藤 明、坂本照夫、今泉 勉
心臓, 2012 - Augmented neovascularization with magnetized endothelial progenitor cells in rats with hind-limb ischemia.
Koiwaya H, Sasaki K, Ueno T, Yokoyama S, Toyama Y, Ohtsuka M, Nakayoshi T, Mitsutake Y, Imaizumi T
J Mol Cell Cardiol, Jul. 2011 - Early outgrowth EPCs generation is reduced in patients with Buerger’s disease.
Katsuki Y, Sasaki K, Toyama Y, Ohtsuka M, Koiwaya H, Nakayoshi T, Imaizumi T
Clin Res Cardiol, Jan. 2011 - 閉塞した人工血管バイパスグラフトに対するPTAにより加療した閉塞性動脈硬化症の1例 Successful Percutaneous Transluminal Angioplasty (PTA) for the Total Occlusion of Synthetic Graft in the Patient with Arteriosclerosis Obliterans (ASO):Case Report
仲吉孝晴、佐々木健一郎、横山晋二、金谷誠司、香月与志夫、外山康之、大塚昌紀、小岩屋宏、光武良亮、上野高史
CVIT Jpn Ed, 2009 - Characterization of differences of inflammatory markers and lymphocyte subsets at culprit lesions in patients with stable angina and acute myocardial infarction.
Satoh S, Mori E, Yokoyama S, Kimura Y, Sagara Y, Mori T, Sugihara M, Tanaka N, Shimizu T, Inoue H, Ikeda J, Nakayoshi T, Morii J, Aso A, Nakamura T, Matsumoto T, Uesugi N, Ueda Y, Makino N, Hiyamuta K
Japanese Journal of Interventional Cardiology, 2008 - 奇異なガリウムシンチ像を呈した心臓原発悪性リンパ腫の一例
田原宣広、仲吉孝晴、甲斐久史、今泉 勉
The Circulation Frontier, 2005 - Disappearance of cardiac gallium uptake after corticosteroid therapy for sarcoidosis.
Tahara N, Kai H, Nakayoshi T, Ikeda S, Miyazaki H, Sugano R, Nagata T, Yamamoto K, Imaizumi T
Clin Cardiol, Oct. 2004
- DES留置後の血管反応の探求 血管内視鏡から考える
仲吉 孝晴
Coronary Intervention, Sep. 2017 - XI.急性冠症候群の臨床(ST上昇型心筋梗塞を除く) 5.急性冠症候群の治療 (1)薬物療法
仲吉孝晴、知花英俊、上野高史
日本臨牀「最新冠動脈疾患学 下」, 2016 - 第3世代DESのhealing
仲吉孝晴、上野高史
TOPIC2016シラバス, 2016 - 地方2次病院での医原性冠動脈解離による心肺停止に対してドクターヘリにて専門医とPCPS搬送を行い救命できた1症例
仲吉 孝晴; 外山 康之; 横山 晋二; 佐々木 健一郎; 上野 高史; 高松 学; 佐藤 明; 坂本 照夫; 今泉 勉
心臓, Aug. 2012
- 閉塞した人工血管のPTAにより加療したASOの一例
仲吉 孝晴、佐々木 健一郎、金谷 誠司、横山 晋二、香月 与志夫、外山 康之、大塚 昌紀、小岩屋 宏、光武 良亮、上野 高史
JACCT&JSIC 平成20年度九州合同地方会, Aug. 2008
■ Research Themes
- FOXO4-knockdown suppresses oxidative stress-induced apoptosis of early pro-angiogenic cells and augments their neovascularization capacities in ischemic limbs
Grant-in-Aid for Young Scientists (B)
Kurume University
2011 - 2013
