Long-term efficacy of endoscopic endonasal transsphenoidal marsupialization using a nasoseptal mucosal flap for petrous apex cholesterol granuloma: systematic review and two case reports
Makoto Hoshino; Kiyohiko Sakata; Sosho Kajiwara; Ryota Mihashi; Taku Ohkubo; Aya Hashimoto; Yusuke Otsu; Takeharu Ono; Hirohito Umeno; Motohiro Morioka
European Archives of Oto-Rhino-Laryngology, 12 Jan. 2026

Surgical trapping and everolimus therapy for a giant internal carotid aneurysm in pediatric tuberous sclerosis complex: case report and literature review.
Kajiwara S; Otsu Y; Kikuchi J; Sakata K; Hamamoto Y; Hirohata M; Nakamura H; Morioka M
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 01 Dec. 2025

Cerebral vasospasm following clipping of unruptured middle cerebral artery aneurysms: a case report and literature review.
Otsu Y; Miyagi K; Takashima C; Kikuchi J; Kajiwara S; Negoto T; Orito K; Sakata K; Hirohata M; Morioka M
Acta neurochirurgica, 08 Sep. 2025

Prophylactic barbiturate step-down infusion therapy has similar and favorable effects in elderly and non-elderly patients with severe traumatic brain injuries
Sosho Kajiwara; Yu Hasegawa; Jin Kikuchi; Kiyohiko Sakata; Tetsuya Negoto; Yukihiko Nakamura; Takayuki Kawano; Yusuke Otsu; Yoshikuni Kotaki; Hideo Nakamura; Masaru Hirohata; Motohiro Morioka
Brain Hemorrhages, Aug. 2025

Temporal Base Transdural Anastomosis in Moyamoya Disease: A Potential Association with Posterior Cerebral Artery Involvement and Clinical Importance.
Otsu Y; Kajiwara S; Kikuchi J; Negoto T; Orito K; Sakata K; Tanoue S; Hirohata M; Morioka M
Neurologia medico-chirurgica, 16 Jul. 2025

Stereotactic Evacuation Performed During the Subacute Phase Improves Functional Independence Measurement Scores in Patients With Putaminal Hemorrhage.
Eto T; Otsu Y; Yamakawa Y; Yamashita S; Kuramoto T; Kawaguchi E; Hasegawa Y; Sakata K; Morioka M
Cureus, 02 May 2025

Impact of Clazosentan on Vasospasm Reduction and Functional Recovery after Aneurysmal Subarachnoid Hemorrhage.
Kajiwara S; Kawano T; Hasegawa Y; Nakamura Y; Sakata K; Kikuchi J; Hirohata M; Morioka M
Neurologia medico-chirurgica, 25 Nov. 2024

Rare Segmental Agenesis of Internal Carotid Artery without Rete-Like Collaterals: A Case Report.
Otsu Y; Yamakawa Y; Eto T; Yamashita S; Kuramoto T; Sakata K; Tanoue S; Hirohata M; Morioka M
Journal of neuroendovascular therapy, 03 Aug. 2024

Clinical and radiographic characteristics of patients with non-functioning pituitary adenomas categorized according to their serum prolactin concentration: novel predictors of postoperative transient diabetes insipidus following surgery.
Sakata K; Hashimoto A; Takeshige N; Orito K; Nagayama A; Ashida K; Nomura M; Morioka M
Endocrine, 25 Apr. 2024

Increased expression of leucine‐rich α‐2 glycoprotein 1 as a predictive biomarker of favorable progression‐free survival in meningioma
Mayuko Moritsubo; Takuya Furuta; Junko Miyoshi; Satoru Komaki; Kiyohiko Sakata; Hiroaki Miyoshi; Motohiro Morioka; Koichi Ohshima; Yasuo Sugita
Neuropathology, Apr. 2024

A Ruptured Aneurysm of the Transdural Anastomotic Artery Occurring at the Temporal Base in Moyamoya Disease: Case Report and Literature Review.
Otsu Y; Kikuchi J; Nakahara Y; Yoshitake H; Kajiwara S; Sakata K; Morioka M
NMC case report journal, 19 Mar. 2024

Emergent Revascularization After Transposition of an Unexpected Intraosseous Anomalous Subarcuate Loop During Vestibular Schwannoma Surgery: A Case Report
Kiyohiko Sakata; Aya Hashimoto; Hidenobu Yoshitake; Sosho Kajiwara; Kimihiko Orito; Hideo Nakamura; Motohiro Morioka
Neurosurgery Practice, Sep. 2023

Visual-evoked potential predicts the efficacy of the optical canal decompression for traumatic optic nerve neuropathy showing blindness: A case report.
Otsu Y; Komaki S; Takeshige N; Sakata K; Morioka M
Surgical neurology international, 14 Jul. 2023

Effects of Microvascular Decompression on Pain Relief and Quality of Life in Late Elderly Patients with Trigeminal Neuralgia.
Otsu Y; Kajiwara S; Hashimoto A; Sakata K; Negoto T; Hasegawa Y; Nakamura H; Hirohata M; Morioka M
Neurologia medico-chirurgica, 06 Apr. 2023

Successful Treatment of Pure Aqueductal Pilomyxoid Astrocytoma and Arrested Hydrocephalus With Endoscopic Tumor Resection Followed by Chemotherapy: A Case Report and Technical Considerations
Kiyohiko Sakata; Aya Hashimoto; Yoshikuni Kotaki; Hidenobu Yoshitake; Shoko Shimokawa; Satoru Komaki; Hideo Nakamura; Takuya Furuta; Motohiro Morioka
Neurosurgery Practice, Mar. 2023

Bold-S Signs on Computed Tomography Angiography Are Sensitive Markers for Diagnosing Subcortical Hemorrhage Due to Dural Arteriovenous Fistulae on Emergent Admission.
Ohkubo T; Kajiwara S; Hasegawa Y; Hashimoto A; Takeuchi Y; Orito K; Kawano T; Fujimori K; Sakata K; Hirohata M; Morioka M
Neurologia medico-chirurgica, 05 Jan. 2023

Endoscopic aqueductal membrane fenestration was effective for intractable hydrocephalus after removal of a nongerminomatous germ cell tumor exhibiting growing teratoma syndrome: a case report.
Kajiwara S; Nakamura H; Sakata K; Komaki S; Negoto T; Morioka M
BMC pediatrics, 28 Nov. 2022

Relationship between Transient Cortical Blindness and Contrast Medium Leakage That Occurs after Endovascular Treatment of Posterior Circulation Aneurysms.
Orito K; Kajiwara S; Takeuchi Y; Sakata K; Abe T; Tanoue S; Uchiyama Y; Hirohata M; Morioka M
Journal of neuroendovascular therapy, 10 Aug. 2022

Neurosurgical Treatment of Patients with Posterior Fossa Acute Subdural Hematoma Right after Cardiac Surgery.
Kikuchi J; Orito K; Sakata K; Yamamoto M; Hasegawa Y; Shojima T; Tayama E; Morioka M
Neurologia medico-chirurgica, 29 Mar. 2022

Primary Pituitary Adenoid Cystic Carcinoma: A Rare Salivary Gland-Like Tumor in the Sella
Kiyohiko Sakata; Takeharu Ono; Motohisa Koga; Jin Kikuchi; Satoru Komaki; Jun Akiba; Etsuyo Ogo; Yasuo Sugita; Hirohito Umeno; Motohiro Morioka
Head and Neck Pathology, Dec. 2021

Early postoperative prediction of both disease remission and long-term disease control in acromegaly using the oral glucose tolerance test
Kiyohiko Sakata; Yui Nagata; Nobuyuki Takeshige; Jin Kikuchi; Masato Shikata; Kenji Ashida; Masatoshi Nomura; Motohiro Morioka
Hormones, 18 Sep. 2021

Subarachnoid hemorrhage due to developmental venous anomaly: A case report
Yu Niwa; Jin Kikuchi; Nobuyuki Takeshige; Yuko Baba; Kimihiko Orito; Kiyohiko Sakata; Yu Hasegawa; Motohiro Morioka
Brain Hemorrhages, Sep. 2021

Efficacy of a Novel Prophylactic Barbiturate Therapy for Severe Traumatic Brain Injuries: Step-down Infusion of a Barbiturate with Normothermia.
Kajiwara S; Hasegawa Y; Negoto T; Orito K; Kawano T; Yoshitomi M; Sakata K; Takeshige N; Yamakawa Y; Jono H; Saito H; Hirayu N; Takasu O; Hirohata M; Morioka M
Neurologia medico-chirurgica, 01 Jun. 2021

Long-term outcomes of endoscopic third ventriculostomy for Blake’s pouch cyst in adults
Nobuyuki Takeshige; Hisaaki Uchikado; Hidenobu Yoshitake; Tetsuya Negoto; Munetake Yoshitomi; Kiyohiko Sakata; Motohiro Morioka
Clinical Neurology and Neurosurgery, Jan. 2021

Endoscopic third ventriculostomy for myelomeningocele-related hydrocephalus after shunt failure: Long-term outcome in a series of 8 patients.
Takeshige N; Uchikado H; Nakashima D; Negoto T; Nagase S; Yoshitomi M; Sakata K; Morioka M
Clinical neurology and neurosurgery, 04 Dec. 2020

Pituitary Gangliocytoma Producing TSH and TRH: A Review of “Gangliocytomas of the Sellar Region”
Kiyohiko Sakata; Kana Fujimori; Satoru Komaki; Takuya Furuta; Yasuo Sugita; Kenji Ashida; Masatoshi Nomura; Motohiro Morioka
The Journal of Clinical Endocrinology & Metabolism, 01 Oct. 2020

Pasireotide-induced hyperglycemia in a patient with Cushing's disease: Potential use of sodium-glucose cotransporter 2 inhibitor and glucagon-like peptide-1 receptor agonist for treatment.
Shikata M; Ashida K; Goto Y; Nagayama A; Iwata S; Yano M; Hasuzawa N; Hara K; Mawatari K; Sakata K; Tsuruta M; Wada N; Nomura M
Clinical case reports, 13 Aug. 2020

Novel method of intraoperative ocular movement monitoring using a piezoelectric device: experimental study of ocular motor nerve activating piezoelectric potentials (OMNAPP) and clinical application for skull base surgeries
Kiyohiko Sakata; Keiko Suematsu; Nobuyuki Takeshige; Yui Nagata; Kimihiko Orito; Naohisa Miyagi; Naoki Sakai; Tsunekazu Koseki; Motohiro Morioka
Neurosurgical Review, 12 Feb. 2020

Endoscopic Endonasal Removal of Primary/Recurrent Meningiomas in the Medial Optic Canal: Surgical Technique and Long-Term Visual Outcome
Kiyohiko Sakata; Nobuyuki Takeshige; Yui Nagata; Hidenobu Yoshitake; Satoru Komaki; Naohisa Miyagi; Motohiro Morioka
Operative Neurosurgery, Nov. 2019

Sagittal diffusion-weighted imaging in preventing the false-negative diagnosis of acute brainstem infarction: Confirmation of the benefit by anatomical characterization of false-negative lesions.
Takeshige N; Aoki T; Sakata K; Kajiwara S; Negoto T; Nagase S; Tanoue S; Uchiyama Y; Hirohata M; Abe T; Morioka M
Surgical neurology international, 20 Sep. 2019

Malignant progression of an extraventricular neurocytoma arising from the VIIIth cranial nerve: A case report and literature review.
Sugita Y; Furuta T; Komaki S; Ohshima K; Sakata K; Morioka M
Neuropathology : official journal of the Japanese Society of Neuropathology, 26 Dec. 2018

Salvage surgery for a locally persistent or recurrent tumour in maxillary cancer patients who have undergone radiotherapy and concomitant intra-arterial cisplatin: implications for surgical margin assessment.
Ono T; Sakata K; Tanaka N; Hashiguchi S; Migita H; Kiyokawa K; Morioka M; Kurita T; Sato K; Takeshige N; Umeno H
International journal of oral and maxillofacial surgery, 15 Nov. 2018

Predictive Value of Leakage Signs for Pure Brain Contusional Hematoma Expansion.
Orito K; Hirohata M; Nakamura Y; Yamamoto M; Takeshige N; Aoki T; Hattori G; Sakata K; Takeuchi Y; Uzu H; Takasu O; Abe T; Uchiyama Y; Morioka M
Journal of neurotrauma, 01 Mar. 2018

Double pituitary adenomas associated with persistent trigeminal artery: a rare case report and the review of literature.
Miyagi N; Doi R; Kuramoto T; Sakata K; Tahara S; Sugita Y; Morioka M
Neurosurgical review, 27 Oct. 2017

Treatment Outcomes of Locally Advanced Squamous Cell Carcinoma of the Ethmoid Sinus Treated with Anterior Craniofacial Resection or Chemoradiotherapy.
Ono T; Tanaka N; Umeno H; Sakata K; Morioka M; Ohmaru Y; Rikimaru H; Koga N; Kiyokawa K; Chitose SI; Shin B; Aso T; Etoh H; Abe T
Case reports in oncology, 01 Jan. 2017

Advantage of Extended Craniofacial Resection for Advanced Malignant Tumors of the Nasal Cavity and Paranasal Sinuses: Long-Term Outcome and Surgical Management
Kiyohiko Sakata; Akiteru Maeda; Hideaki Rikimaru; Takeharu Ono; Noriyuki Koga; Nobuyuki Takeshige; Takashi Tokutomi; Hirohito Umeno; Kensuke Kiyokawa; Motohiro Morioka
World Neurosurgery, May 2016

Leakage Sign for Primary Intracerebral Hemorrhage: A Novel Predictor of Hematoma Growth.
Orito K; Hirohata M; Nakamura Y; Takeshige N; Aoki T; Hattori G; Sakata K; Abe T; Uchiyama Y; Sakamoto T; Morioka M
Stroke, 01 Mar. 2016

Primary meningeal melanocytoma of the sellar region: review of the literature and differential diagnosis with special reference to angiographical features.
Sakata K; Miyoshi J; Takeshige N; Komaki S; Miyagi N; Nakashima S; Morioka M; Sugita Y
Pituitary, 01 Oct. 2015

DNA mismatch repair protein (MSH6) correlated with the responses of atypical pituitary adenomas and pituitary carcinomas to temozolomide: the national cooperative study by the Japan Society for Hypothalamic and Pituitary Tumors.
Hirohata T; Asano K; Ogawa Y; Takano S; Amano K; Isozaki O; Iwai Y; Sakata K; Fukuhara N; Nishioka H; Yamada S; Fujio S; Arita K; Takano K; Tominaga A; Hizuka N; Ikeda H; Osamura RY; Tahara S; Ishii Y; Kawamata T; Shimatsu A; Teramoto A; Matsuno A
The Journal of clinical endocrinology and metabolism, 30 Jan. 2013

Sensitivity and usefulness of anti-phosphohistone-H3 antibody immunostaining for counting mitotic figures in meningioma cases.
Fukushima S; Terasaki M; Sakata K; Miyagi N; Kato S; Sugita Y; Shigemori M
Brain tumor pathology, 27 Oct. 2009

Impact of combination therapy with repeat surgery and temozolomide for recurrent or progressive glioblastoma multiforme: a prospective trial.
Terasaki M; Ogo E; Fukushima S; Sakata K; Miyagi N; Abe T; Shigemori M
Surgical neurology, 01 Sep. 2007

[A surgically treated case with a ruptured bacterial aneurysm of the middle cerebral arterial bifurcation following occlusion].
Yamaguchi S; Sakata K; Nakayama K; Orito K; Ikeda A; Arakawa M; Shigemori M
No shinkei geka. Neurological surgery, 01 May 2004

[A case of embolic infarction originating from extracranial vertebral artery stenosis by cervical spondylosis at C5/6: its pathogenesis and surgical treatment].
Yamaguchi S; Sakata K; Nakayama K; Shigemori M
No shinkei geka. Neurological surgery, 01 Oct. 2003

Autocrine signaling through Ras regulates cell survival activity in human glioma cells: potential cross-talk between Ras and the phosphatidylinositol 3-kinase-Akt pathway.
Sakata K; Kato S; Fox JC; Shigemori M; Morimatsu M
Journal of neuropathology and experimental neurology, 01 Nov. 2002

Inhibition of autocrine fibroblast growth factor signaling by the adenovirus-mediated expression of an antisense transgene or a dominant negative receptor in human glioma cells in vitro.
Aoki T; Kato S; Fox JC; Okamoto K; Sakata K; Morimatsu M; Shigemori M
International journal of oncology, 01 Sep. 2002

The biochemical analysis of neurotransmitters in central neurocytomas.
Sugita Y; Yamada S; Sugita S; Sakata K; Morimatsu M; Shigemori M
International journal of molecular medicine, 01 May 2001

Acute focal demyelinating disease simulating brain tumors: histopathologic guidelines for an accurate diagnosis.
Sugita Y; Terasaki M; Shigemori M; Sakata K; Morimatsu M
Neuropathology : official journal of the Japanese Society of Neuropathology, 01 Mar. 2001

脳内出血の転帰改善を目指した選択的・積極的・短時間降圧療法の開発
基盤研究(C)
久留米大学
01 Apr. 2021 - 31 Mar. 2025

脳循環変化に伴う有害事象を予測する、新たな術中モニタリングシステムの開発
基盤研究(C)
久留米大学
01 Apr. 2020 - 31 Mar. 2025

Development of new devise of continuous olfactory mucosa stimulation for intraoperative monitoring and treatment of cognitive dysfunction
Grant-in-Aid for Scientific Research (C)
Kurume University
01 Apr. 2019 - 31 Mar. 2023

Experimental study and clinical application of intraoperative ocular motor nerve monitoring using a new piezoelectric device
Grant-in-Aid for Scientific Research (C)
Kurume University
01 Apr. 2016 - 31 Mar. 2019

頭蓋内に発生した脳実質外腫瘍、特に頭蓋底腫瘍の治療を専門としています。良性腫瘍のことが多いため手術成績そのものが重要な領域ですが、副鼻腔癌の頭蓋内進展例や術後に化学療法や放射線治療を必要とするような腫瘍も含まれますので、脳腫瘍全般の知識と経験が必要です。また安全で最大限の摘出ができるように、術中脳神経モニタリングに対しても積極的に行っています。

頭蓋底手術手技内視鏡手術手技脳神経モニタリング