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The Biostatistics Center
Assistant Professor
Research activity information
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■ Paper
- Optimal strategies for surgical resection of pancreatic body cancer: A multi-institutional cohort study
Asahi Sato; Takayuki Anazawa; Kazuyuki Nagai; Yosuke Kasai; Kei Yamane; Kenzo Nakano; Akiyoshi Nakakura; Toshihiko Masui; Kojiro Nakamura; Kazuhiko Kitaguchi; Takefumi Yazawa; Yuhei Hamaguchi; Yusuke Uemoto; Kentaro Yasuchika; Koshiro Morino; Koji Doi; Toshiyuki Hata; Takashi Komatsubara; Yukihiro Okuda; Ryo Kamimura; Koji Kitamura; Etsuro Hatano
Surgery, Feb. 2026, [Reviewed] - Nivolumab with definitive chemoradiotherapy for oesophageal squamous cell carcinoma (NOBEL): a multicentre, single-arm, phase 2 feasibility trial
Motoo Nomura; Katsuyuki Sakanaka; Juko Shimizu; Shinya Ohashi; Chikatoshi Katada; Akinori Watanabe; Yusuke Amanuma; Keiko Minashi; Ken Kato; Takashi Kojima; Kengo Nagashima; Ihhwa Kim; Harue Tada; Akiyoshi Nakakura; Manabu Muto
eClinicalMedicine, Jan. 2026, [Reviewed] - Impact of Surgical Resection on Hepatocellular Carcinoma Following Systemic Drug Therapy: A Multicenter Retrospective Observational Study
Takamichi Ishii; Junichi Shindoh; Ikuo Nakamura; Seiko Hirono; Masaki Wakasugi; Akihiko Ichida; Takashi Hamada; Hajime Matsushima; Takahiro Nishio; Yukio Tokumitsu; Hidenori Takahashi; Yuji Morine; Shinichiro Yamada; Akiyoshi Nakakura; Susumu Eguchi; Kiyoshi Hasegawa; Etsuro Hatano
Hepatology Research, 23 Aug. 2025, [Reviewed] - Efficacy of Simple Oral Nutritional Supplements versus Usual Care in Postoperative Patients with Gastric Cancer
Kohei Ueno; Tatsuto Nishigori; Yukinari Tokoro; Kenjiro Hirai; Akira Miki; Yoshito Yamashita; Seiichiro Kanaya; Kosuke Toda; Dai Manaka; Yasutaka Nakanishi; Yosuke Kinjo; Akiyoshi Nakakura; Kyoichi Hashimoto; Michihiro Yamamoto; Yuichiro Kawamura; Hiroshi Okabe; Masazumi Sakaguchi; Takatsugu Kan; Eiji Tanaka; Atsushi Itami; Masato Kondo; Hironori Kawada; Shigeo Hisamori; Takashi Sakamoto; Shintaro Okumura; Shigeru Tsunoda; Koya Hida; Nobuaki Hoshino; Hisatsugu Maekawa; Kazutaka Obama
Annals of Surgery, 07 Aug. 2025, [Reviewed] - Activation of anti-donor CD8 alloimmune response in clinically diagnosed acute rejection early after living-donor lobar lung transplantation and its impact on outcome
Satona Tanaka; Naoki Tanimine; Akiyoshi Nakakura; Koichiro Uchida; Ichiro Sakanoue; Hidenao Kayawake; Mamoru Takahashi; Shigeto Nishikawa; Yojiro Yutaka; Yoshito Yamada; Akihiro Ohsumi; Masatsugu Hamaji; Daisuke Nakajima; Toyofumi F. Chen-Yoshikawa; Yuka Tanaka; Hideki Ohdan; Hiroshi Date
Transplant Immunology, May 2025, [Reviewed] - Phase II study of carboplatin plus weekly paclitaxel with bevacizumab for non-squamous, non-small cell lung cancer with idiopathic interstitial pneumonia (Hanshin Cancer Group IP002)
Nobuyuki Katakami; Kazuma Nagata; Akiyoshi Nakakura; Tadashi Okamoto; Toshihiko Kaneda; Masahide Oki; Kana Watanabe; Takaaki Tokito; Yoshihiro Amano; Motohiro Tamiya; Satoshi Morita; Yukimasa Hatachi
Japanese Journal of Clinical Oncology, 23 Sep. 2024, [Reviewed] - Adjuvant Chemotherapy After Neoadjuvant Therapy and Surgery for Non-Small Cell Lung Cancer.
Ryo Miyata; Masatsugu Hamaji; Akiyoshi Nakakura; Hiroaki Ozasa; Masashi Kobayashi; Makoto Sonobe; Ryo Miyahara; Akihiro Aoyama; Ryutaro Kikuchi; Hiroshi Date
Annals of thoracic surgery short reports, Sep. 2024, [Reviewed] - Combination of risk alleles of PNPLA3, TM6SF2, and HSD17B13 of donors can predict recurrence of steatotic liver disease after liver transplantation
Kenta Makino; Takamichi Ishii; Satoshi Ogiso; Akiyoshi Nakakura; Takahiro Nishio; Ken Fukumitsu; Elena Yukie Uebayashi; Fumiaki Munekage; Hiroshi Horie; Kentaro Iwaki; Takashi Ito; Etsuro Hatano
Hepatology Research, 20 Jun. 2024, [Reviewed] - A Deep Learning–Based Assay for Programmed Death Ligand 1 Immunohistochemistry Scoring in Non–Small Cell Lung Carcinoma: Does it Help Pathologists Score?
Hiroaki Ito; Akihiko Yoshizawa; Kazuhiro Terada; Akiyoshi Nakakura; Mariyo Rokutan-Kurata; Tatsuhiko Sugimoto; Kazuya Nishimura; Naoki Nakajima; Shinji Sumiyoshi; Masatsugu Hamaji; Toshi Menju; Hiroshi Date; Satoshi Morita; Ryoma Bise; Hironori Haga
Modern Pathology, Jun. 2024, [Reviewed] - Protocol of a phase II study to evaluate the efficacy and safety of deep-inspiration breath-hold daily online adaptive radiotherapy for centrally located lung tumours (PUDDING study).
Noriko Kishi; Masahiro Yoneyama; Hiroyuki Inoo; Minoru Inoue; Hiraku Iramina; Akiyoshi Nakakura; Tomohiro Ono; Hideaki Hirashima; Takanori Adachi; Norimasa Matsushita; Makoto Sasaki; Takahiro Fujimoto; Mitsuhiro Nakamura; Yukinori Matsuo; Takashi Mizowaki
Radiation oncology (London, England), 08 Mar. 2024, [Reviewed] - Quantitative analysis of the effect of docetaxel-induced edema on quality of life in patients with breast cancer and related factors: a prospective cohort study.
Tomoko Izawa; Ami Kobayashi; Masahiro Kawashima; Nobuko Kawaguchi-Sakita; Akiyoshi Nakakura; Yuki Kataoka; Kenichiro Shide; Yukiko Mori; Kazuhiro Yamazaki; Masakazu Toi; Harue Arao
BMC women's health, 07 Mar. 2024, [Reviewed] - Is routine lymph node dissection recommended for liver resection of intrahepatic cholangiocarcinoma? A systematic review and meta-analysis
Takamichi Ishii; Kentaro Iwaki; Akiyoshi Nakakura; Tomoaki Yoh; Yoichiro Uchida; Etsuro Hatano
HPB, Mar. 2024, [Reviewed] - Peripheral nerve regeneration following scaffold-free conduit transplant of autologous dermal fibroblasts: a non-randomised safety and feasibility trial
Ryosuke Ikeguchi; Tomoki Aoyama; Takashi Noguchi; Mika Ushimaru; Yoko Amino; Akiyoshi Nakakura; Noriko Matsuyama; Shiori Yoshida; Momoko Nagai-Tanima; Keiko Matsui; Yasuyuki Arai; Yoko Torii; Yudai Miyazaki; Shizuka Akieda; Shuichi Matsuda
Communications Medicine, 26 Jan. 2024, [Reviewed] - Comparison of cisplatin-based versus standard preoperative chemotherapy in patients with operable triple-negative breast cancer: propensity score matching and inverse probability of treatment weighting analysis.
Ayane Yamaguchi; Kosuke Kawaguchi; Kana Kawanishi; Yurina Maeshima; Akiyoshi Nakakura; Tatsuki R Kataoka; Sachiko Takahara; Shunsaku Nakagawa; Atsushi Yonezawa; Masahiro Takada; Masahiro Kawashima; Nobuko Kawaguchi-Sakita; Takeshi Kotake; Eiji Suzuki; Hanako Shimizu; Masae Torii; Satoshi Morita; Hiroshi Ishiguro; Masakazu Toi
Breast cancer research and treatment, 21 Dec. 2023, [Reviewed] - Analysis of the characteristics and outcomes of patients with pseudomyxoma peritonei of appendiceal origin treated with curative-intent surgery
Yasuyuki Kamada; Koya Hida; Yutaka Yonemura; Akiyoshi Nakakura; Toshiyuki Kitai; Akiyoshi Mizumoto; Shinya Yoshida; Yukinari Tokoro; Kazutaka Obama
Surgical Oncology, Dec. 2023, [Reviewed] - Is the anterior approach recommended for liver resection of hepatocellular carcinoma? A systematic review and meta-analysis.
Takamichi Ishii; Kentaro Iwaki; Akiyoshi Nakakura; Yoichiro Uchida; Takashi Ito; Etsuro Hatano
Journal of hepato-biliary-pancreatic sciences, 20 Nov. 2023, [Reviewed] - Biomarker‐based Bayesian randomized clinical trial design for identifying a target population
Yasuo Sugitani; Satoshi Morita; Akiyoshi Nakakura; Hideharu Yamamoto
Statistics in Medicine, 19 Apr. 2023, [Reviewed] - Real‑world effect of bevacizumab and eribulin on metastatic breast cancer using a propensity score matching analysis
Koshi Matsui; Mitsuharu Earashi; Akemi Yoshikawa; Wataru Fukushima; Zensei Nozaki; Kaeko Oyama; Kiichi Maeda; Akiyoshi Nakakura; Satoshi Morita; Tsutomu Fujii
Molecular and Clinical Oncology, 13 Jan. 2023, [Reviewed] - Postoperative tegafur-uracil for stage I lung adenocarcinoma: first real-world data with an exploratory subgroup analysis.
Ryo Miyata; Masatsugu Hamaji; Akiyoshi Nakakura; Satoshi Morita; Yumeta Shimazu; Masashi Ishikawa; Hidenao Kayawake; Toshi Menju; Yasuto Sakaguchi; Makoto Sonobe; Mamoru Takahashi; Akihiro Aoyama; Ryota Sumitomo; Cheng-Long Huang; Tomoya Kono; Ryo Miyahara; Akira Matsumoto; Hiromichi Katakura; Takahisa Fukada; Hiroaki Sakai; Masashi Kobayashi; Norihito Okumura; Naoki Date; Takuji Fujinaga; Ei Miyamoto; Tatsuo Nakagawa; Hiroshi Date
Surgery today, Jan. 2023, [Reviewed] - Risk factors for the recurrence of relapsing polychondritis
Tsuneyasu Yoshida; Hajime Yoshifuji; Mirei Shirakashi; Akiyoshi Nakakura; Kosaku Murakami; Koji Kitagori; Shuji Akizuki; Ran Nakashima; Koichiro Ohmura; Akio Morinobu
Arthritis Research & Therapy, Dec. 2022, [Reviewed] - Propensity score-based analysis of stereotactic body radiotherapy, lobectomy and sublobar resection for stage I non-small cell lung cancer
Noriko Kishi; Yukinori Matsuo; Toshi Menju; Masatsugu Hamaji; Akiyoshi Nakakura; Hideki Hanazawa; Keiichi Takehana; Hiroshi Date; Takashi Mizowaki
Journal of Radiation Research, 11 Jul. 2022, [Reviewed] - 小型肺癌に対する治療 手術vs定位放射線治療(SBRT) Propensity score-weighted analysisを用いたI期NSCLC高齢患者における治療成績の検討
濱路 政嗣; 岸 徳子; 松尾 幸憲; 毛受 暁史; 中倉 章祥; 花澤 豪樹; 竹花 恵一; 田中 里奈; 山田 義人; 豊 洋次郎; 大角 明宏; 中島 大輔; 溝脇 尚志; 伊達 洋至
日本胸部外科学会定期学術集会, Oct. 2021 - The benefit of self-management skills in gynaecological cancer patients in preventing clinically manifest lymphedema. Journal of Lymphoedema
Tomoko Izawa; Sena Yamamoto; Akiyoshi Nakakura; Harue Tada; Harue Arao
Journal of Lymphoedema, Sep. 2021, [Reviewed] - Lymph node dissection in thymic carcinomas and neuroendocrine carcinomas.
Masatsugu Hamaji; Mitsugu Omasa; Takao Nakanishi; Akiyoshi Nakakura; Satoshi Morita; Ei Miyamoto; Tatsuo Nakagawa; So Miyahara; Makoto Sonobe; Mamoru Takahashi; Yasuji Terada; Kyoko Hijiya; Ryota Sumitomo; Cheng-Long Huang; Fumitsugu Kojima; Tsuyoshi Shoji; Naoki Date; Ryo Miyata; Michiharu Suga; Ryo Nakanobo; Kenzo Kawakami; Akihiro Aoyama; Hiroshi Date
Interactive cardiovascular and thoracic surgery, 26 Jul. 2021, [Reviewed] - Repurposing bromocriptine for Aβ metabolism in Alzheimer’s disease (REBRAnD) study: randomised placebo-controlled double-blind comparative trial and open-label extension trial to investigate the safety and efficacy of bromocriptine in Alzheimer’s disease with presenilin 1 (PSEN1) mutations
Takayuki Kondo; Haruhiko Banno; Taro Okunomiya; Yoko Amino; Kayoko Endo; Akiyoshi Nakakura; Ryuji Uozumi; Akemi Kinoshita; Harue Tada; Satoshi Morita; Hidehiro Ishikawa; Akihiro Shindo; Ken Yasuda; Yosuke Taruno; Takakuni Maki; Takashi Suehiro; Kohji Mori; Manabu Ikeda; Koji Fujita; Yuishin Izumi; Kazutomi Kanemaru; Kenji Ishii; Kazue Shigenobu; Yumiko Kutoku; Yoshihide Sunada; Shinobu Kawakatsu; Shunji Shiota; Toshifumi Watanabe; Osamu Uchikawa; Ryosuke Takahashi; Hidekazu Tomimoto; Haruhisa Inoue
BMJ Open, Jun. 2021, [Reviewed] - Are volume-dependent parameters in positron emission tomography predictive of postoperative recurrence after resection in patients with thymic carcinoma?
Masatsugu Hamaji; Sho Koyasu; Mitsugu Omasa; Akiyoshi Nakakura; Satoshi Morita; Tatsuo Nakagawa; So Miyahara; Ryo Miyata; Yuhei Yokoyama; Kenzo Kawakami; Michiharu Suga; Mamoru Takahashi; Yasuji Terada; Yusuke Muranishi; Ryo Miyahara; Ryota Sumitomo; Cheng-Long Huang; Akihiro Aoyama; Yutaka Takahashi; Hiroshi Date
Surgery today, 13 Jun. 2020, [Reviewed] - Biodegradable Flow Diverter for the Treatment of Intracranial Aneurysms: A Pilot Study Using a Rabbit Aneurysm Model.
Hidehisa Nishi; Akira Ishii; Isao Ono; Yu Abekura; Hiroyuki Ikeda; Daisuke Arai; Yukihiro Yamao; Masakazu Okawa; Takayuki Kikuchi; Akiyoshi Nakakura; Susumu Miyamoto
Journal of the American Heart Association, 15 Oct. 2019, [Reviewed]
- Missing Data and Measurement Errors: Statistical Approach to Incomplete Data Analysis
Kyoji Furukawa; Natsumi Kumano; Yurika Kawazoe; Akiyoshi Nakakura
Japanese Journal of Biometrics, 30 Nov. 2025 - Bayesian trial design to identify a sensitive subpopulation in non-proportional hazard settings
Akiyoshi Nakakura
2025 JSM Proceedings, Oct. 2025 - Effect of nivolumab combined with definitive chemoradiotherapy on response rate for esophageal cancer: An immune active intrinsic subtype could be its biomarker-The NOBEL trial
Manabu Muto; Motoo Nomura; Katsuyuki Sakanaka; Juko Shimizu; Shinya Ohashi; Akinori Watanabe; Chikatoshi Katada; Yusuke Amanuma; Keiko Minashi; Ken Kato; Takashi Kojima; Kengo Nagashima; Ihhwa Kim; Harue Tada; Akiyoshi Nakakura; Hiroki Sasaki
JOURNAL OF CLINICAL ONCOLOGY, 01 Jun. 2024 - 小型肺癌に対する治療 手術vs定位放射線治療(SBRT) Propensity score-weighted analysisを用いたI期NSCLC高齢患者における治療成績の検討
濱路 政嗣; 岸 徳子; 松尾 幸憲; 毛受 暁史; 中倉 章祥; 花澤 豪樹; 竹花 恵一; 田中 里奈; 山田 義人; 豊 洋次郎; 大角 明宏; 中島 大輔; 溝脇 尚志; 伊達 洋至
日本胸部外科学会定期学術集会, Oct. 2021 - Propensity score-weighted analysisを用いたI期NSCLC高齢患者における治療成績の検討
岸 徳子; 松尾 幸憲; 毛受 暁史; 濱路 政嗣; 中倉 章祥; 花澤 豪樹; 竹花 恵一; 伊達 洋至; 溝脇 尚志
日本癌治療学会学術集会抄録集, Oct. 2020
- Bayesian trial design to identify a sensitive subpopulation in non-proportional hazard settings
Akiyoshi Nakakura
2025 Joint Statistical Meetings, 06 Aug. 2025 - 観察スケジュールがMixed-effects models for repeated measures (MMRM) の検出力に与える影響
中倉 章祥; 室谷 健太
2025年度 日本計量生物学会年会, 15 May 2025 - 3つ以上の治療法を比較する場合の傾向スコア逆確率重み付け解析
中倉 章祥; 岸本 淳司
SASユーザー総会2024, 19 Sep. 2024 - Biomarker-based Bayesian Randomized Clinical Trial Design for Identifying a Target Population
中倉章祥; 森田智司; 山本英晴; 杉谷康雄
第5回 かごしまデータ科学シンポジウム, 09 Dec. 2023 - Biomarker-based Bayesian Randomized Clinical Trial Design for Identifying a Target Population
Akiyoshi Nakakura; Satoshi Morita; Yasuo Sugitani; Hideharu Yamamoto
5th International Conference on Econometrics and Statistics (EcoSta 2022), 05 Jun. 2022 - Biomarker-based Bayesian randomized clinical trial for population finding with efficient reduction of sample size
Akiyoshi Nakakura; Satoshi Morita; Yasuo Sugitani; Hideharu Yamamoto
42nd Annual Conference of the International Society for Clinical Biostatistics, 19 Jul. 2021
