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海江田 信二郎
内科学講座（呼吸器・神経・膠原病内科部門）
准教授
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- Periostin Is a Biomarker of Rheumatoid Arthritis-Associated Interstitial Lung Disease
Matama G, Okamoto M, Fujimoto K, Johkoh T, Tominaga M, Mukae H, Sakamoto N, Komiya K, Umeki K, Komatsu M, Shimizu Y, Takahashi K, Tokisawa S, Zaizen Y, Matsuo N, Nouno T, Kaieda S, Ida H, Izuhara K, Hoshino T.
J Clin Med., 2023年11月 - Combination of Prednisolone and Calcineurin Inhibitors Prevents Lung Function Decline in Patients with Anti-aminoacyl-tRNA Synthetase Antibody-Positive Polymyositis/Dermatomyositis
Yorishima Y, Tominaga M, Fujimoto K, Nagata S, Sumi A, Chikasue T, Okamoto M, Kaieda S, Matama G, Zaizen Y, Obara H, Kakuma T, Ida H, Kawayama T, Hoshino T.
Kurume Med J., 2023年11月 - IL-18 receptor-α signalling pathway contributes to autoantibody-induced arthritis via neutrophil recruitment and mast cell activation.
Kaieda S, Kinoshita T, Chiba A, Miyake S, Hoshino T
Modern Rheumatology, 2023年05月 - Share Positive Autoantibody Is Associated with Malignancies in Patients with Idiopathic Interstitial Pneumonias.
Koga T, Okamoto M, Satoh M, Fujimoto K, Zaizen Y, Chikasue T, Sumi A, Kaieda S, Matsuo N, Matama G, Nouno T, Tominaga M, Yatera K, Ida H, Hoshino T
Biomedicines, 2022年10月 - Clinical Characteristics of Anti-TIF-1γ Antibody-Positive Dermatomyositis Associated with Malignancy
Harada Y, Tominaga M, Iitoh E, Kaieda S, Koga T, Fujimoto K, Chikasue T, Obara H, Kakuma T, Ida H, Kawayama T, Hoshino T.
J Clin Med., 2022年05月 - Cancer-associated Dermatomyositis with Histiocytic Sarcoma
Tsutsumi M, Shimasaki Y, Koga T, Kaieda S.
Intern Med., 2022年01月 - Epstein-Barr Virus-Related Lymphoproliferative Disorders-Associated Polymyositis in a Patient With Rheumatoid Arthritis
Kaieda S, Koga T, Yamada K, Ida H.
J Clin Rheumatol., 2021年12月 - MEFV E148Q variant is more associated with familial Mediterranean fever when combined with other non-exon 10 MEFV variants in Japanese patients with recurrent fever
Fujimoto K, Hidaka Y, Koga T, Kaieda S, Yamasaki S, Nakashima M, Hoshino T, Yamamoto K, Nishikomori R, Ida H.
Mod Rheumatol., 2021年11月 - Clinical phenotypes and genetic analyses for diagnosis of systemic autoinflammatory diseases in adult patients with unexplained fever
Hidaka Y, Fujimoto K, Matsuo N, Koga T, Kaieda S, Yamasaki S, Nakashima M, Migita K, Nakayama M, Ohara O, Hoshino T, Nishikomori R, Ida H
Mod Rheumatol., 2021年05月 - Risk Prediction Modeling Based on a Combination of Initial Serum Biomarker Levels in Polymyositis/Dermatomyositis-Associated Interstitial Lung Disease
Gono T, Masui K, Nishina N, Kawaguchi Y, Kawakami A, Ikeda K, Kirino Y, Sugiyama Y, Tanino Y, Nunokawa T, Kaneko Y, Sato S, Asakawa K, Ukichi T, Kaieda S, Naniwa T, Okano Y, Kuwana M; the Multicenter Retrospective Cohort of Japanese Patients with Myositis-Associated ILD (JAMI) Investigators.
Arthritis Rheumatol, 2021年04月 - Mast cells can produce transforming growth factor β1 and promote tissue fibrosis during the development of Sj?gren's syndrome-related sialadenitis
Kaieda S, Fujimoto K, Todoroki K, Abe Y, Kusukawa J, Hoshino T, Ida H
Mod Rheumatol., 2021年 - Subcutaneous Cheek Nodule Associated with Granulomatosis with Polyangiitis
Hayashi M, Kaieda S, Kawaguchi A, Tsutsumi M, Harada Y, Koga T, Akiba J, Hoshino T, Ida H.
Intern Med., 2021年 - CD163 deficiency facilitates lipopolysaccharide-induced inflammatory responses and endotoxin shock in mice
Fujiwara Y, Ohnishi K, Horlad H, Saito Y, Shiraishi D, Takeya H, Yoshii D, Kaieda S, Hoshino T, Komohara Y.
Clin Transl Immunology., 2020年09月 - Evaluation of usefulness in surfactant protein D as a predictor of mortality in myositis-associated interstitial lung disease
Kaieda S, Gono T, Masui K, Nishina N, Sato S, Kuwana M; A Multicenter Retrospective Cohort of Japanese Patients with Myositis-associated ILD (JAMI) investigators.
PLoS One., 2020年06月 - Clinical and Genetic Analysis of 22 Japanese Patients with Familial Mediterranean Fever: An Examination of MEFV and 10 Other Genes Related to Autoinflammatory Syndromes
Fujimoto K, Hidaka Y, Koga T, Kaieda S, Yamasaki S, Nakashima M, Hoshino T, Ida H.
Intern Med., 2020年 - Signal intensity of superb micro-vascular imaging associates with the activity of vascular inflammation in Takayasu arteritis
Ito S, Tahara N, Hirakata S, Kaieda S, Tahara A, Maeda-Ogata S, Bekki M, Sugiyama Y, Honda A, Igata S, Kuromatsu R, Nakashima O, Fukumoto Y.
Nucl Cardiol., 2020年01月 - Elevation of pulmonary CD163 + and CD204 + macrophages is associated with the clinical course of idiopathic pulmonary fibrosis patients
Nouno T, Okamoto M, Ohnishi K, Kaieda S, Tominaga M, Zaizen Y, Ichiki M, Momosaki S, Nakamura M, Fujimoto K, Fukuoka J, Shimizu S, Komohara Y, Hoshino T.
J Thorac Dis., 2019年09月 - Juxta-vertebral Lesions Associated with Granulomatosis with Polyangiitis.
Yoshida Y, Kaieda S, Furuta T, Ida H.
Intern Med., 2019年09月 - A retrospective study of the tolerability of nintedanib for severe idiopathic pulmonary fibrosis in the real world
Nakamura M, Okamoto M, Fujimoto K, Ebata T, Tominaga M, Nouno T, Zaizen Y, Kaieda S, Tsuda T, Kawayama T Hoshino T.
Ann Transl Med., 2019年06月 - Attenuated Airway Eosinophilic Inflammations in IL-38 Knockout Mouse Model.
atsuoka M, Kawayama T, Tominaga M, Kaieda S, Tokunaga Y, Kaku Y, Imaoka H, Kinoshita T, Okamoto M, Akiba J, Hoshino T.
Kurume Med J., 2019年05月 - Clinical Characteristics of Relapsing Polychondritis: A Report of 8 Cases in Japan
ajiri M, Tominaga M, Kinoshita T, Nakamura M, Kaieda S, Okamoto M, Ida H, Kawayama T, Hoshino T.
Kurume Med J., 2019年05月 - Low positive titer of anti-melanoma differentiation-associated gene 5 antibody is not associated with a poor long-term outcome of interstitial lung disease in patients with dermatomyositis
Sakamoto S, Okamoto M, Kaieda S, Fujimoto K, Nagata S, Tominaga M, Nakamura M, Zaizen Y, Nouno T, Koga T, Kawayama T, Kuwana M, Ida H, Hoshino T.
Respir Investig, 2018年11月 - Limbic Encephalitis in Association with Systemic Lupus Erythematosus.
Sugi S, Kaieda S, Irie KI, Ida H.
Internal Medicine, 2018年10月 - Initial predictors of poor survival in myositis-associated interstitial lung disease: a multicentre cohort of 497 patients.
Sato S, Masui K, Nishina N, Kawaguchi Y, Kawakami A, Tamura M, Ikeda K, Nunokawa T, Tanino Y, Asakawa K, Kaneko Y, Gono T, Ukichi T, Kaieda S, Naniwa T, Kuwana M; JAMI investigators.
Rheumatology (Oxford), 2018年07月 - The co-existence of Lemierre's syndrome and Bezold's abscesses due to Streptococcus constellatus: A case report
Yaita K, Sugi S, Hayashi M, Koga T, Ebata T, Sakai Y, Kaieda S, Ida H, Watanabe H.
Medicine (Baltimore), 2018年06月 - Successful Treatment of Rapidly Progressive Unclassifiable Idiopathic Interstitial Pneumonia with Anti-melanoma Differentiation-associated Gene-5 Antibody by Intensive Immunosuppressive Therapy
Koga T, Kaieda S, Okamoto S, Masuda K, Fujimoto K,Sakamoto S, Nakamura M, Tominaga M, Kawayama T, Fujimoto K, Hoshino T, Ida H
Internal Medicine, 2018年04月 - 皮膚筋炎の診断を契機に子宮体癌が発見された腫瘍随伴症候群の1例
藤崎可菜、松隈健、河野光一郎、久保沙代、那須洋紀、桃嵜正啓、寺田貴武、西尾真、津田尚武、駒井幹、海江田信二郎、牛嶋公生
福岡産科婦人科学会雑誌, 2018年 - Overexpression of IL-38 protein in anticancer drug-induced lung injury and acute exacerbation of idiopathic pulmonary fibrosis
Tominaga M, Okamoto M, Kawayama T, Matsuoka M, Kaieda S, Sakazaki Y, Kinoshita T, Mori D, Inoue A, Hoshino T
Respiratory Investgation, 2017年09月 - The Successful Treatment of Myeloperoxidase Antineutrophil Cytoplasmic Antibody-positive Hypertrophic Pachymeningitis in Patients with the Limited Form of Granulomatosis with Polyangiitis Using Methotrexate: Two Case Reports
Kaieda S, Yoshida N, Minezaki M, Ushijima S, Wakasugi D,Miura S, Uchiyama Y, Ida H, Hoshino T
Internal Medicine, 2017年 - Association of anti-aminoacyl-transfer RNA synthetase antibody and anti-melanoma differentiation-associated gene 5 antibody with the therapeutic response of polymyositis/dermatomyositis-associated interstitial lung disease.
Yoshida N, Okamoto M, Kaieda S, Fujimoto K, Ebata T, Tajiri M, Nakamura M, Tominaga M, Wakasugi D, Kawayama T, Kuwana M, Mimori T, Ida H, Hoshino T.
Respir Investig, 2017年 - A retrospective cohort study of outcome in systemic sclerosis-associated interstitial lung disease.
Okamoto M, Fujimoto K, Sadohara J, Furuya K, Kaieda S, Miyamura T, Suematsu E, Kitasato Y, Kawayama T, Ida H, Ichiki M, Hoshino T.
Respiratory Investigation, 2016年 - An Autopsy Case of Anti-melanoma Differentiation-associated Gene-5 Antibody-positive Clinical Amyopathic Dermatomyositis Complicated by Rapidly Progressive Interstitial Lung Disease.
Yoshida N, Kaieda S, Tomozoe K, Tajiri M, Wakasugi D, Okamoto M, Tominaga M, Ida H, Hoshino T
Internal medicine, 2016年 - Magnetic Resonance Imaging of Dermatomyositis with Bilateral Involvement of the Erector Spinae Muscle. 2016:39(3);93-94.
Kaieda S, Okamoto M, Miura S, Ida H.
Ewha Med J., 2016年 - Successful treatment of macrophage activation syndrome in a patient with dermatomyositis by combination with immunosuppressive therapy and plasmapheresis.
Kaieda S, Yoshida N, Yamashita F, Okamoto M, Ida H, Hoshino T, Fukuda T
Modern Rheumatology, 2015年 - A novel missense mutation of RYR1 in familial idiopathic hyper CK-emia.
Sano K, Miura S, Fujiwara T, Fujioka R, Yorita A, Noda K, Kida H, Azuma K, Kaieda S, Yamamoto K, Taniwaki T, Fukumaki Y, Shibata H.
J Neurol Sci, 2015年 - IL-38: A new factor in rheumatoid arthritis.
Kaieda S, Takenaka S, Kawayama T, Matsuoka M, Kaku Y, Kinoshita T, Sakazaki Y, Okamoto M, Tominaga M, Kanesaki K, Chiba A, Miyake S, Ida H, Hoshino T.
Biochemistry and Biophysics Reports., 2015年 - Cricothyroid perichondritis in a patient with dermatomyositis.
Kaieda S, Yoshida N, Idemoto A, Ida H.
Intern Medicine, 2014年 - A subcutaneous panniculitis-like T-cell lymphoma mimicking dermatomyositis
Kaieda S, Idemoto A, Yoshida N, Ida H.
Intern Medicine, 2014年 - IL-33/ST2 axis promotes mast cell survival via BCLXL.
Kaieda S, Wang JX, Ameri S, Fishgal N, Dwyer D, Dellinger A, Kepley CL, Gurish MF, Nigrovic PA.
Proc Natl Acad Sci U S A, 2014年 - An autopsy case of refractory vasculo-Behcet’s disease
Kaieda S, Zaizen Y, Nomura Y, Okabe K, Kage M, Ida H, Hoshino T, Fukuda T
Modern Rheumatology, 2013年04月 - A Case of Late-onset Systemic Lupus Erythematosus with Severe Anemia
Matsumoto M, Kaieda S, Honda S, Ida H, Hoshino T, Fukuda T
Kurume Medical Journal, 2013年02月 - Interleukin-33 primes mast cells for activation by IgG immune complexes.
Kaieda S, Wang J, Shnayder R, Fishgal N, Hei H, Lee RT, Stevens RL, Nigrovic PA.
PLoS One, 2012年10月 - Successful treatment of rectal ulcers in a patient with systemic lupus erythematosus using corticosteroids and tacrolimus
Kaieda S, Kobayashi T, Moroki M, Honda S, Yuge K, Kawano H, Mitsuyama K, Sata M, Ida H, Hoshino T, Fukuda T
Modern Rheumatology, 2012年10月 - Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1).
Kaieda S, Shin K, Nigrovic PA, Seki K, Lee RT, Stevens RL, Lee DM
J Biol Chem, 2010年09月 - Activation of invariant natural killer T cells by synthetic glycolipid ligands suppresses autoantibody-induced arthritis
Kaieda S, Tomi C, Oki S, Yamamura T, Miyake S
Arthritis Rheum, 2007年06月
- 関節炎におけるマスト細胞の関与
海江田信二郎
久留米醫學會雜誌, 2020年 - 肥満細胞は関節リウマチの疾患活動性と相関し自己抗体産生に寄与する
海江田信二郎
リウマチ科, 2020年 - The Successful Treatment of Myeloperoxidase Antineutrophil Cytoplasmic Antibody-positive Hypertrophic Pachymeningitis in Patients with the Limited Form of Granulomatosis with Polyangiitis Using Methotrexate: Two Case Reports.
Shinjiro Kaieda, Naomi Yoshida, Takuma Koga, Kyoko Fujimoto, Hiroaki Ida, Tomoaki Hoshino.
The 18TH International vasculitis and ANCA workshop. Tokyo Japan, 2017., 2017年03月
- Mast Cells Contribute to the Development of Sialadenitis Associated with Sj?gren’s Syndrome via Inducing Tissue Fibrosis by TGFβ Production.
Kaieda S, Fujimoto K, Ida H.
2020 American College of Rheumatology Convergence. November 5-9, 2020 (All Virtual)., 2020年11月 - Surfactant Protein D as a Useful Predictor for Mortality in Myositis-associated Interstitial Lung Disease: A Dimorphic Model Based on anti-MDA5 Antibody.
Kaieda S, Gono T, Masui K, Nishina N, Sato S, Kuwana M.
2019 Annual Scientific Meeting on American College of Rheumatology, Atlanta, 2019年11月 - シェーグレン症候群に対するマスト細胞の関与
海江田信二郎、藤本京子、古賀琢眞、林真樹子、吉田裕美、井田弘明
学会名;第63回日本リウマチ学会総会, 2019年04月 - Involvement of Mast Cells in the Pathogenesis of Sj?gren’s Syndrome By Induction of Tissue Fibrosis Via Fibroblast Collagen Synthesis.
Shinjiro Kaieda, Kyoko Fujimoto, Masaki Tominaga, Masaki Okamoto, Tomoaki Hoshino, Hiroaki Ida.
82th Annual Scientific Meeting on American College of Rheumatology, Chicago, USA. October 19-24, 2018., 2018年10月 - マスト細胞のシェーグレン症候群への関与
海江田信二郎、藤本京子、岡元昌樹、富永正樹、星野友昭、井田弘明
第62回日本リウマチ学会総会, 2018年04月 - Mast Cells Are Involved in the Pathogenesis of Sj?gren Syndrome By Inducing Tissue Fibrosis.
Shinjiro Kaieda, Kyoko Fujimoto, Masaki Okamoto, Masaki Tominaga, Tomoaki Hoshino, Hiroaki Ida.
81th Annual Scientific Meeting on American College of Rheumatology, San Diego, USA. 2017., 2017年10月 - Involvement of CD163-Positive Macrophages in the Pathogenesis of Arthritis Via Modulation of Inflammatory Cytokine and Chemokine Expression in the Synovium of a Murine Model.
Kaieda S, Ida H, Hoshino T.
80th Annual Scientific Meeting on American College of Rheumatology, Washington D.C, USA. 2016., 2016年10月 - Involvement of M2 Macrophages in the Pathogenesis of Arthritis in a Mouse Model.
Kaieda S, Yoshida N, Kunitake Y, Wakasugi D, Fujiwara Y, Komahara Y, Ida H, Hoshino T.
79th Annual Scientific Meeting on American College of Rheumatology, San Francisco, USA. 2015., 2015年11月 - IL-38: A New Factor in Rheumatoid Arthritis.
Kaieda S, Takenaka S, Hoshino T.
12th World Congress on Inflammation. Boston USA、2015., 2015年08月 - IL-38: A New Factor in Rheumatoid Arthritis.
Kaieda S, Kanezaki K, Yoshida N, Kunitake Y, Ida H and Tomoaki Hoshino.
78th Annual Scientific Meeting on American College of Rheumatology, Boston, USA. 2014 ., 2014年11月 - The involvement of mast cells in the development of lung fibrosis via modulating pulmonary fibroblast immune function.
Kiaeda S, Tajiri M, Okamoto M, Yoshida N, Ida H, Hoshino T, Fukuda T.
7th Annual Scientific Meeting on American College of Rheumatology, 2013年11月 - 関節炎におけるsynovial fibroblast-mast cellの相互作用解析
海江田信二郎、井田弘明
第33回日本炎症・再生医学会, 2012年07月 - Functional interaction between synovial mast cells and fibroblast-like synoviocytes via IL-33 and its receptor ST2.
Kaieda S
第56回日本リウマチ学会総会学術集会, 2012年04月 - IL-33 Contributes to joint Inflammation Via mast sell inmmune function
Kaieda S
第55回日本リウマチ学会・学術集会, 2011年07月 - 膠原病関連間質性肺炎と特発性間質性肺炎との差異:気管支肺胞洗浄分析から
田尻守拡 井田弘明 海江田信二郎 本多靖洋 福田孝昭
第55回日本リウマチ学会総会・学術集会, 2011年07月
■ 研究者からの一言アピール
■ 関心を持って取組んでいる活動
