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Murai Yoshinaka
Division of Integrated Autonomic Department of Physiology
Associate Professor
Researcher information
■ Research Keyword
■ Research Theme
- Patch clamp method
- electrophysiology
- ニューロン・シナプス機能連関
- Slice Patch-clamp method
- Electrophysiology
- Function of Neural and Synaptic Activities
- Life sciences, Clinical pharmacy
- Life sciences, Physiology, 神経生理
- Life sciences, Neuroscience - general, シナプス伝達
■ Research Theme
Career
■ Career
- Oct. 2009 - Present
Kurume University, School of Medicine, School of Medicine, Associate Professor - Jul. 2004 - Sep. 2009
Kurume University, School of Medicine, School of Medicine, 講師 - Apr. 2000 - Apr. 2004
Hokkaido University, Graduate School of Dental Medicine, 助手 - Oct. 1998 - Mar. 2000
Kumamoto University, 医学部薬理学第ニ講座, 特別研究員、財団法人ヒューマンサイエンス リサーチレジデント
- Apr. 1994 - Mar. 1998, Kyushu University, Graduate School, Division of Medical Sciences, Department of Physiology
Research activity information
■ Paper
- The inhibition of evoked excitatory postsynaptic potentials produced by ammonium chloride in rat hippocampal CA1 neurons.
Naomitsu Kameyama; Yoshinaka Murai; Eiichiro Tanaka
Heliyon, Dec. 2020, [Reviewed] - Activation of cathepsin L contributes to the irreversible depolarization induced by oxygen and glucose deprivation in rat hippocampal CA1 neurons
Shogo Kikuta; Yoshinaka Murai; Eiichiro Tanaka
NEUROSCIENCE LETTERS, Jan. 2017, [Reviewed] - Clinical Trials in Acute Ischemic Stroke
Kiyoshi Kikuchi; Eiichiro Tanaka; Yoshinaka Murai; Salunya Tancharoen
CNS DRUGS, Oct. 2014, [Reviewed] - Potential of the Angiotensin Receptor Blockers (ARBs) Telmisartan, Irbesartan, and Candesartan for Inhibiting the HMGB1/RAGE Axis in Prevention and Acute Treatment of Stroke
Kiyoshi Kikuchi; Salunya Tancharoen; Takashi Ito; Yoko Morimoto-Yamashita; Naoki Miura; Ko-ichi Kawahara; Ikuro Maruyama; Yoshinaka Murai; Eiichiro Tanaka
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Sep. 2013, [Reviewed] - The Efficacy of Edaravone (Radicut), a Free Radical Scavenger, for Cardiovascular Disease
Kiyoshi Kikuchi; Salunya Tancharoen; Nobuyuki Takeshige; Munetake Yoshitomi; Motohiro Morioka; Yoshinaka Murai; Eiichiro Tanaka
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Jul. 2013, [Reviewed] - The alteration of glutamate clearance in astrocytes derived from MeCP2-null mouse
Yasunori Okabe; Tomoyuki Takahashi; Chiaki Mitsumasu; Yoshinaka Murai; Toyojiro Matsuishi; Eiichiro Tanaka
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2013, [Reviewed] - Edaravone (Radicut), a free radical scavenger, is a potentially useful addition to thrombolytic therapy in patients with acute ischemic stroke.
Kikuchi K; Miura N; Kawahara KI; Murai Y; Morioka M; Lapchak PA; Tanaka E
Biomedical reports, Jan. 2013, [Reviewed] - Clinical Neuroprotective Drugs for Treatment and Prevention of Stroke
Kiyoshi Kikuchi; Hisaaki Uchikado; Motohiro Morioka; Yoshinaka Murai; Eiichiro Tanaka
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Jun. 2012, [Reviewed] - Activation of protein kinase A and C prevents recovery from persistent depolarization produced by oxygen and glucose deprivation in rat hippocampal neurons
Y. Murai; Y. Okabe; E. Tanaka
JOURNAL OF NEUROPHYSIOLOGY, May 2012, [Reviewed] - Neural development of methyl-CpG-binding protein 2 null embryonic stem cells: A system for studying Rett syndrome
Yasunori Okabe; Akira Kusaga; Tomoyuki Takahashi; Chiaki Mitsumasu; Yoshinaka Murai; Eiichiro Tanaka; Hideho Higashi; Toyojiro Matsuishi; Ken-ichiro Kosai
BRAIN RESEARCH, Nov. 2010, [Reviewed] - Thiamylal antagonizes the inhibitory effects of dorsal column stimulation on dorsal horn activities in humans
Eiichiro Tanaka; Toshiyuki Tobita; Yoshinaka Murai; Yasunori Okabe; Aya Yamada; Tatsuhiko Kano; Hideho Higashi; Koki Shimoji
NEUROSCIENCE RESEARCH, Aug. 2009, [Reviewed] - Two opposing roles of 4-AP-sensitive K+ current in initiation and invasion of spikes in rat mesencephalic trigeminal neurons
Mitsuru Saito; Yoshinaka Murai; Hajime Sato; Yong-Chul Bae; Tadashi Akaike; Masahiko Takada; Youngnam Kang
JOURNAL OF NEUROPHYSIOLOGY, Oct. 2006, [Reviewed] - Neuroprotective mechanisms of lidocaine against in vitro ischemic insult of the rat hippocampal CA1 pyramidal neurons
S Niiyama; E Tanaka; S Tsuji; Y Murai; M Satani; H Sakamoto; K Takahashi; M Kuroiwa; A Yamada; M Noguchi; H Higashi
NEUROSCIENCE RESEARCH, Nov. 2005, [Reviewed] - Excitatory GABAergic synaptic potentials in the mesencephalic trigerninal nucleus of adult rat in vitro
Y Yokomizo; Y Murai; E Tanaka; H Inokuchi; J Kusukawa; H Higashi
NEUROSCIENCE RESEARCH, Apr. 2005, [Reviewed] - Orexins cause depolarization via nonselective cationic and K+ channels in isolated locus coeruleus neurons
Y Murai; T Akaike
NEUROSCIENCE RESEARCH, Jan. 2005, [Reviewed] - Functional, metabolic, and histological changes of vascular tissues after warm ischemia.
Moriyama. S; Utoh. J; Murai. Y; Hagiwara. S; Kunitomo. R; Nishi. K; Kitamura. N
Ann Thorac Cardiovasc Surg., 2001, [Reviewed] - Noradrenaline receptor-mediated potentiation of caffeine-induced Ca2+-activated K+ currents in bovine ciliary muscle cells
T Okuda; N Tokutomi; Y Tokutomi; Y Murai; A Negi; K Nishi
CURRENT EYE RESEARCH, 2001, [Reviewed] - The prostaglandin E series modulates high-voltage-activated calcium channels probably through the EP3 receptor in rat paratracheal ganglia
Y Ito; Y Murai; H Ishibashi; H Onoue; N Akaike
NEUROPHARMACOLOGY, 2000, [Reviewed] - Preferential inhibition of L- and N-type calcium channels in the rat hippocampal neurons by cilnidipine
Y Murai; H Uneyama; H Ishibashi; K Takahama; N Akaike
BRAIN RESEARCH, Jan. 2000, [Reviewed] - Effect of nilvadipine on the voltage-dependent Ca2+ channels in rat hippocampal CA1 pyramidal neurons
H Ishibashi; Y Murai; N Akaike
BRAIN RESEARCH, Nov. 1998, [Reviewed] - Acetylcholine modulation of high-voltage-activated calcium channels in the neurones acutely dissociated from rat paratracheal ganglia
Y Murai; H Ishibashi; N Akaike; Y Ito
BRITISH JOURNAL OF PHARMACOLOGY, Apr. 1998 - Different effect of oxytocin on membrane potential of supraoptic oxytocin neurons in virgin female and male rats in vitro
M Yoshinaka; T Nakashima; S Miyata; T Kiyohara
NEUROSCIENCE RESEARCH, Jan. 1998 - Ca2+-activated K+ currents in rat locus coeruleus neurons induced by experimental ischemia, anoxia, and hypoglycemia
Y Murai; H Ishibashi; S Koyama; N Akaike
JOURNAL OF NEUROPHYSIOLOGY, Nov. 1997 - Effects of 5-(4-piperidyl) isoxazol-3-ol (4-PIOL), a GABA(A) receptor partial agonist, on recombinant human GABA(A) receptors
SE WesthHansen; K Noguchi; MR Witt; Y Murai; M Nielsen; N Akaike
NEUROSCIENCE LETTERS, Jul. 1997 - Two components of metabotropic glutamate responses in acutely dissociated CA3 pyramidal neurons of the rat
N Harata; J Katayama; Y Takeshita; Y Murai; N Akaike
BRAIN RESEARCH, Mar. 1996 - NALOXONE SUPPRESSES THE RISING PHASE OF FEVER INDUCED BY INTERFERON-ALPHA
T NAKASHIMA; T MURAKAMI; Y MURAI; T HORI; S MIYATA; T KIYOHARA
BRAIN RESEARCH BULLETIN, 1995
- Potential of the Angiotensin Receptor Blockers (ARBs) Telmisartan, Irbesartan, and Candesartan for Inhibiting the HMGB1/RAGE Axis in Prevention and Acute Treatment of Stroke. (vol 14, pg 18899, 2013)
Kiyoshi Kikuchi; Salunya Tancharoen; Takashi Ito; Yoko Morimoto-Yamashita; Naoki Miura; Ko-ichi Kawahara; Ikuro Maruyama; Yoshinaka Murai; Eiichiro Tanaka
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Apr. 2014 - 脳内神経ペプチドであるオレキシンの睡眠障害治療薬としての可能性を探る基礎的アプローチ
久留米医学会雑誌, 2010
- Apr. 2025 - Present
学校法人高尾学園 高尾看護専門学校 - Apr. 2023 - Present
久留米大学人間健康学部スポーツ医学科 - Apr. 2023 - Present
久留米大学医学部看護学科大学院修士課程 - Apr. 2023 - Present
九州大学医学部 - Apr. 2023 - Present
医療福祉専門学校緑生館 専攻看護学科 - Apr. 2023 - Present
久留米大学医学部医学科 - Sep. 2022 - Present
久留米大学医学部医学科 - May 2004 - Present
久留米大学医学部医学科 - Apr. 2004 - Present
久留米大学医学部看護学科 - Apr. 2016 - Mar. 2023
- Apr. 2016 - Mar. 2023
- Apr. 2006 - Mar. 2016
久留米大学医学部医学科 - Apr. 2006 - Mar. 2016
久留米大学医学部医学科
- Apr. 1990 - Present
日本神経科学会 - Apr. 1990 - Present
日本生理学会 - Apr. 1990 - Present
The Japanese Neuroscience Society - Apr. 1990 - Present
The Physiological Society of Japan
- 虚血性神経細胞死に関与する細胞内機序
2008 - Activation of protein kinase A contributes to the persistent depolarization induced by in vitro ischemia
2008 - 機械的単離法を用いた三叉神経中脳路核ニューロンのシナプス電流解析
2002 - GABAergic synaptic responses recorded from neurons in rat mesencephalic trigeminal nucleus in vitro.
2002 - 三叉神経中脳路核ニューロンの活動電位生成に対するA型K+チャネルの関与
2001 - A role of A-type K+ channel in regulation of spike generation in Rat mesencephalic trigeminal neurons.
2001
- The study about ion channel disorder of central nervous system in Rett's syndrome
Grant-in-Aid for Young Scientists (B)
Kurume University
Apr. 2015 - Mar. 2019 - 統合失調症の発現過程にオキシトシンはどのように関与するのか
Apr. 2014 - Mar. 2016 - Glial cells differentiation of MeCP2 deficient ES/iPS cells and pathophysiology of Rett syndrome
Grant-in-Aid for Scientific Research (C)
Kurume University
Apr. 2013 - Mar. 2016 - Effects of monoamine on the prefrontal cortical neurons and amygdaloid nuclei neurons
Grant-in-Aid for Scientific Research (C)
Kurume University
Apr. 2011 - Mar. 2013 - Generation of iPS cells derived form an Rett syndrome model mouse and drug screening for Rett syndrome using MeCP2 deficient iPS cells
Grant-in-Aid for Scientific Research (C)
Kurume University
2010 - 2012 - Health effect evaluation based on characteristics of nanoparticles
Grant-in-Aid for Scientific Research (C)
Kurume University
2007 - 2009 - Dose aromatase regulate the feeding behavior and induce the sexual difference on appetite?
Grant-in-Aid for Scientific Research (C)
Kurume University
2007 - 2008 - 虚血性神経細胞死に関与する細胞内機序
2008 - Activation of protein kinase A contributes to the persistent depolarization induced by in vitro ischemia
2008 - Do androgen receptors contribute to the expression of sex differences in the brain?
Grant-in-Aid for Scientific Research (C)
Kurume University
2006 - 2007 - 機械的単離法を用いた三叉神経中脳路核ニューロンのシナプス電流解析
2002 - GABAergic synaptic responses recorded from neurons in rat mesencephalic trigeminal nucleus in vitro
2002 - 三叉神経中脳路核ニューロンの活動電位生成に対するA型K+チャネルの関与
2001 - A role of A-type K+ channel in regulation of spike generation in Rat mesencephalic trigeminal neurons
2001
